Evidence map›Paper›PMID 35437746›Full record

ArticleImmunology2022

Cell origin and niche availability dictate the capacity of peritoneal macrophages to colonize the cavity and omentum.

Pieter A Louwe, Stuart J Forbes, Cécile Bénézech, Clare Pridans, Stephen J Jenkins

Open access · hybridAbstract read
In one paragraph

Article in Immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Pleural macrophages translocate to the lung during infection to promote improved influenza outcomes.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  9. Article
  10. Article
  11. Peritoneal resident macrophages in tumor metastasis and immunotherapy.Frontiers in cell and developmental biology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Pieter A LouweQueens Medical Research Institute, University of Edinburgh Centre for Inflammation Research, Edinburgh, UK.ORCID 0000-0002-8451-1451
Stuart J ForbesCentre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK.
Cécile BénézechQueens Medical Research Institute, University of Edinburgh Centre for Cardiovascular Science, Edinburgh, UK.
Clare PridansQueens Medical Research Institute, University of Edinburgh Centre for Inflammation Research, Edinburgh, UK.
Stephen J JenkinsQueens Medical Research Institute, University of Edinburgh Centre for Inflammation Research, Edinburgh, UK.ORCID 0000-0002-0233-5424
Centre for Inflammation Research · GBMRC Centre for Regenerative Medicine · GBThe Queen's Medical Research Institute · GBVIB-UGent Center for Inflammation Research · BE

Funding

Medical Research Council MR/L008076/1Medical Research Council MR/M011542/1Medical Research Council MR/M019969/1Wellcome Trust 108906/Z/15/ZWellcome Trust 203909
6 · The paper itself

Abstract

The relationship between macrophages of the peritoneal cavity and the adjacent omentum remains poorly understood. Here, we describe two populations of omental macrophages distinguished by CD102 expression and use an adoptive cell transfer approach to investigate whether these arise from peritoneal macrophages, and whether this depends upon inflammatory status, the origin of peritoneal macrophages and availability of the omental niches. We show that whereas established resident peritoneal macrophages largely fail to migrate to the omentum, monocyte-derived resident cells readily migrate and form a substantial component of omental CD102

Indexed as

Macrophages, PeritonealOmentumMacrophagesPeritoneal Cavityimmune homeostasisinflammationmacrophageomentumperitonealtrafficking

Identifiers

PMID35437746
PMCPMC7613338
OpenAlexW4224239255

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.