Evidence map›Paper›PMID 35437711›Full record

ReviewSports medicine (Auckland, N.Z.)2022

Muscle Force Contributions to Anterior Cruciate Ligament Loading.

Nirav Maniar, Michael H Cole, Adam L Bryant, David A Opar

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Sports medicine (Auckland, N.Z.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07061314 (Comparison of Lower Limb COP and Muscle Activation During Single-Leg Deadlift Using Elastic and Inelastic Barbells), which is not on this map. Cited by 71 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07061314 nacompletednot on this mapstarted 2025, after this paper: background citation

Comparison of Lower Limb COP and Muscle Activation During Single-Leg Deadlift Using Elastic and Inelastic Barbells

TypeinterventionalSponsorBusan University of Foreign StudiesRan2025 to 2025Enrolled27ConditionsNeuromuscular Control, Functional Training, Lower Limb StabilityArmsElastic Barbell, Inelastic Barbell
3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nirav ManiarSchool of Behavioural and Health Sciences, Australian Catholic University, 17 Young Street, Fitzroy, VIC, 3065, Australia. Nirav.Maniar@acu.edu.au.ORCID http://orcid.org/0000-0002-6180-6003
Michael H ColeSchool of Behavioural and Health Sciences, Australian Catholic University, Brisbane, Australia.
Adam L BryantDepartment of Physiotherapy, Centre for Health, Exercise and Sports Medicine, The University of Melbourne, Melbourne, Australia.
David A OparSchool of Behavioural and Health Sciences, Australian Catholic University, 17 Young Street, Fitzroy, VIC, 3065, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anterior cruciate ligament (ACL) injuries are one of the most common knee pathologies sustained during athletic participation and are characterised by long convalescence periods and associated financial burden. Muscles have the ability to increase or decrease the mechanical loads on the ACL, and thus are viable targets for preventative interventions. However, the relationship between muscle forces and ACL loading has been investigated by many different studies, often with differing methods and conclusions. Subsequently, this review aimed to summarise the evidence of the relationship between muscle force and ACL loading. A range of studies were found that investigated muscle and ACL loading during controlled knee flexion, as well as a range of weightbearing tasks such as walking, lunging, sidestep cutting, landing and jumping. The quadriceps and the gastrocnemius were found to increase load on the ACL by inducing anterior shear forces at the tibia, particularly when the knee is extended. The hamstrings and soleus appeared to unload the ACL by generating posterior tibial shear force; however, for the hamstrings, this effect was contingent on the knee being flexed greater than ~ 20° to 30°. The gluteus medius was consistently shown to oppose the knee valgus moment (thus unloading the ACL) to a magnitude greater than any other muscle. Very little evidence was found for other muscle groups with respect to their contribution to the loading or unloading of the ACL. It is recommended that interventions aiming to reduce the risk of ACL injury consider specifically targeting the function of the hamstrings, soleus and gluteus medius.

Indexed as

Anterior Cruciate LigamentAnterior Cruciate Ligament InjuriesBiomechanical PhenomenaHumansKnee JointMuscle, Skeletal

Identifiers

PMID35437711
PMCPMC9325827

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.