ArticleObstetric medicine2022
Case series of COVID-19 infection in pregnancy complicated by ketoacidosis and symptomatic breathlessness.
Article in Obstetric medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 10 citations in OpenAlex.
- Metabolic acidosis with elevated anion gap and euglycemic ketoacidosis in pregnant and postpartum women with severe Covid-19.Annals of medicine · 2025Observational
- Euglycemic diabetic ketoacidosis and COVID-19 management in a term pregnant patient; a case report.Clinical case reports · 2022Article
- Considerations for women with COVID-19 admitted to hospital.Obstetric medicine · 2022Review
- Starvation ketosis in a pregnant woman with COVID-19: a case report.Endocrinology, diabetes & metabolism case reports · 2022Article
- Diabetic ketoacidosis in patients with SARS-CoV-2: a systematic review and meta-analysis.Diabetology & metabolic syndrome · 2021Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The differential diagnosis of acute shortness of breath in a pregnant woman with COVID-19 is broad. Pregnancy is a ketosis-prone state, which can result in metabolic acidosis and tachypnoea. Methods: We describe four pregnant women with COVID-19 and breathlessness where ketoacidosis was found to contribute to symptomatic tachypnoea. Results: One patient did not have associated COVID-19 pneumonitis, but presented with severe tachypnoea and metabolic acidosis; three women had pneumonitis and metabolic acidosis. Corrective treatment for the metabolic abnormalities resulted in resolution of the ketoacidosis in all cases. No women had coexistent diabetes. Conclusion: This is the first series of COVID-19 in pregnancy complicated by ketoacidosis and symptomatic tachypnoea. Ketoacidosis associated with COVID-19 is an important cause of tachypnoea requiring specific treatment, which should not be overlooked. Potential mechanisms for this are discussed with a framework for interpretation of blood gas results during pregnancy.
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