ReviewHypertension research : official journal of the Japanese Society of Hypertension2022
Blood pressure management for secondary stroke prevention.
Review in Hypertension research : official journal of the Japanese Society of Hypertension, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Development of a high-performing, cost-effective and inclusive Afrocentric predictive model for stroke: a meta-analysis approach.BMC neurology · 2025Pooled it
- A randomized controlled pilot study investigating adherence to blood pressure diaries with personal pictures in stroke follow-up care.Wiener klinische Wochenschrift · 2025Trial
- Knowledge and Practice Regarding Stroke Prevention and Associated Factors Among Hypertensive Patients at Selected Public Hospitals in Addis Ababa, Ethiopia: A Cross-Sectional Study.Health science reports · 2026Article
- Community-Based Hypertension Screening to Prevent Stroke in Underserved Urban Neighborhoods in French Guiana: Protocol for a Quasi-Experimental Study.JMIR research protocols · 2026Article
- Association between multimorbidity and young-onset dementia: a prospective study.BMC public health · 2025Article
- Association between diastolic blood pressure and post-stroke cognitive impairment: a real-world retrospective cohort study.Annals of medicine · 2025Article
- NAT10 induces N4-acetylcytidine modification of AdipoR1-mediated mitochondrial biogenesis against endothelial-to-mesenchymal transition in hypertension.Molecular medicine (Cambridge, Mass.) · 2025Article
- Lipoxins as Modulators of Diseases.Cells · 2025Review
- Impact of transesophageal echocardiogram findings on management of acute ischemic stroke: a retrospective single-institution cohort study.Annals of medicine and surgery (2012) · 2025Article
- Prevalence of Multiple Chronic Conditions in Older Adults with Undiagnosed Mild Cognitive Impairment and Alzheimer's Disease and Related Dementias in Primary Care.Clinical interventions in aging · 2025Article
- Text mining of hypertension researches in the west Asia region: a 12-year trend analysis.Renal failure · 2024Article
- Small vessel disease burden predicts incident stroke and all-cause death, but not acute coronary event.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Observational
- Feasibility of ambulatory blood pressure monitoring to predict cardiovascular outcome in stroke survivors.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Distinct pathophysiology of small vessel disease from atherosclerosis.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Blood pressure management to prevent recurrent stroke: current evidence and perspectives.NPJ cardiovascular health · 2024Review
- miR-193b-3p and miR-346 Exert Antihypertensive Effects in the Rostral Ventrolateral Medulla.Journal of the American Heart Association · 2024Article
- Article
- Causal associations of COVID-19 on neurosurgical diseases risk: a Mendelian randomization study.Human genomics · 2024Article
- Epidemiology, Pathophysiology, and Current Treatment Strategies in Stroke.Cardiology and cardiovascular medicine · 2024Article
- Nocturnal Intermittent Hypoxia and the Risk of Cardiovascular Disease among Japanese Populations: The Circulatory Risk in Communities Study (CIRCS).Journal of atherosclerosis and thrombosis · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypertension is the most important vascular risk factor for stroke; therefore, optimal blood pressure (BP) management is essential for the prevention of recurrent stroke; lowering BP was shown to reduce the risk of recurrent stroke by 25-30%. A recent meta-analysis showed that intensive BP lowering to levels <130/80 mmHg significantly reduced the risk of recurrent stroke compared to standard management with BP levels <140/90 mmHg. The benefit of intensive BP management is evident with regard to a reduced risk of intracranial hemorrhage. Therefore, clinical practice guidelines have established a target BP of <130/80 mmHg. However, the target BP needs to be individualized. A stepped-care approach for cautious BP lowering (usually to levels <140/90 mmHg) is preferred for patients with severe diseases of the major cerebral vessels, who have a high risk of recurrent ischemic stroke. In contrast, more aggressive BP lowering (to levels <120/80 mmHg) tends to benefit patients at high risk of intracranial hemorrhage. The selection of BP management strategies should be guided by the risk of recurrent ischemic and hemorrhagic strokes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.