Evidence map›Paper›PMID 35437117›Full record

ArticleEmerging microbes & infections2022

MCR-1-dependent lipid remodelling compromises the viability of Gram-negative bacteria.

Siyuan Feng, Wanfei Liang, Jiachen Li, Yong Chen, Dianrong Zhou, Lujie Liang, Daixi Lin, Yaxin Li, Hui Zhao, Huihui Du and 6 more

Open access · goldAbstract read
In one paragraph

Article in Emerging microbes & infections, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. The Role ofInfection and drug resistance · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Itaconate induces tolerance ofFrontiers in microbiology · 2024
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Mobile Colistin Resistance (Antibiotics (Basel, Switzerland) · 2023
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 3 countries.

Siyuan FengProgram in Pathobiology, The Fifth Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, People's Republic of China.
Wanfei LiangProgram in Pathobiology, The Fifth Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, People's Republic of China.
Jiachen LiProgram in Pathobiology, The Fifth Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, People's Republic of China.
Yong ChenSchool of Laboratory Medicine, Chengdu Medical College, Chengdu, People's Republic of China.
Dianrong ZhouProgram in Pathobiology, The Fifth Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, People's Republic of China.
Lujie LiangProgram in Pathobiology, The Fifth Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, People's Republic of China.
Daixi LinProgram in Pathobiology, The Fifth Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, People's Republic of China.
Yaxin LiProgram in Pathobiology, The Fifth Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, People's Republic of China.
Hui ZhaoGuangdong Provincial Key Laboratory of Biotechnology for Plant Development, School of Life Sciences, South China Normal University, Guangzhou, People's Republic of China.
Huihui DuCollege of Biology and Food Engineering, Chongqing Three Gorges University, Chongqing, People's Republic of China.
Min DaiSchool of Laboratory Medicine, Chengdu Medical College, Chengdu, People's Republic of China.
Li-Na QinDepartment of Histology and Embryology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, People's Republic of China.
Fan BaiBiomedical Pioneering Innovation Center (BIOPIC), School of Life Sciences, Peking University, Beijing, People's Republic of China.
Yohei DoiUniversity of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Lan-Lan ZhongProgram in Pathobiology, The Fifth Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, People's Republic of China.
Guo-Bao TianProgram in Pathobiology, The Fifth Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, People's Republic of China.
Sun Yat-sen University · CNChengdu Medical College · CNFifth Affiliated Hospital of Sun Yat-sen University · CNChongqing Three Gorges University · CNFujita Health University · JPPeking University · CNSouth China Normal University · CNXizang Minzu University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global dissemination of the mobilized colistin resistance gene,

Indexed as

ColistinEscherichia coli ProteinsGram-Negative BacteriaAnti-Bacterial AgentsDrug Resistance, BacterialEscherichia coliHumansPlasmidsAnti-Bacterial AgentsColistinEscherichia coli ProteinsMCR-1 protein, E colicolistinlipid homeostasisMCR-1outer membrane (OM) permeabilityviability

Identifiers

PMID35437117
PMCPMC9067951
OpenAlexW4224249763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.