Evidence map›Paper›PMID 35437004›Full record

SynthesisInternational journal of obesity (2005)2022

Age at adiposity rebound and the relevance for obesity: a systematic review and meta-analysis.

Jixing Zhou, Fu Zhang, Xiaoyun Qin, Peixuan Li, Yuzhu Teng, Shanshan Zhang, Fangbiao Tao, Kun Huang

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in International journal of obesity (2005), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. BMI profiling for monogenic obesity testing.The Lancet. Child & adolescent health · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Early adiposity rebound: predictors and outcomes.Italian journal of pediatrics · 2024
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jixing ZhouDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Anhui Province, China.
Fu ZhangDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Anhui Province, China.
Xiaoyun QinDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Anhui Province, China.
Peixuan LiDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Anhui Province, China.
Yuzhu TengDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Anhui Province, China.
Shanshan ZhangDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Anhui Province, China.
Fangbiao TaoDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Anhui Province, China.
Kun HuangDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Anhui Province, China. ahmuhuangk@163.com.ORCID 0000-0001-8550-4571

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo understand the sex difference in age at adiposity rebound (AR), integrate the prevalence of early AR (EAR), and provide a quantitative association between early age at AR and overweight/obesity.

methodsLiterature review was conducted in different databases, including the Web of Science, PubMed, EMBASE, Wiley, Chinese National Knowledge Infrastructure, and ScienceDirect databases up to August 2021. Studies that reported data related to AR were considered for inclusion. Pooled effect sizes and their respective 95% confidence intervals (CIs) were calculated using random effects models, depending on the size of heterogeneity. Heterogeneity was tested by using the I

results28 studies with a combined sample size of 106,397 people were included in the final meta-analysis. Girls had a significantly earlier age of AR than boys (mean difference = 3.38 months; 95% CI 2.14-4.63). The overall prevalence of EAR was 40% (95% CI 31% to 50%), and the prevalence in girls was 5% higher than that in boys based on the definition of age at AR < 5.0-5.1 years. The overall pooled prevalence of EAR showed an increasing trend by child's birth year [1934-1973]: 29% (95% CI 22% to 37%), 1991-2001: 35% (95% CI 26% to 44%), and 2002-2009: 52% (95% CI 40-63%). Early age at AR (age at AR < 5.0-5.1 years) was associated with a significantly increased risk of overweight/obesity (OR = 5.07; 95% CI 3.60-7.12), overweight (OR = 3.10; 95% CI 1.69-5.70), and obesity (OR = 6.97; 95% CI 4.32-11.26) from the preschool period to adulthood.

conclusionsThe overall prevalence of EAR is increasing, and girls experience AR earlier than boys. The early age at AR in children may be an early and effective marker of obesity.

Indexed as

AdiposityOverweightAdultBody Mass IndexChildChild, PreschoolFemaleHumansInfantMaleObesityPrevalence

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.