ArticleBMC medical imaging2022
T2 mapping for knee cartilage degeneration in young patients with mild symptoms.
Article in BMC medical imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
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- Region-, zone-, and layer-specific knee cartilage T2 relaxation patterns in sports-active adolescents.European radiology · 2026Article
- Grading knee cartilage degeneration and meniscal injury with combined ACS-accelerated T1ρ and T2 mapping.BMC medical imaging · 2026Article
- Healthy knee cartilage T2 mapping assessed with GRAPPATINI and multi-echo spin-echo (MESE) at 3T: regional values, longitudinal repeatability and method agreement.Quantitative imaging in medicine and surgery · 2026Article
- Two years efficacy and safety outcomes of using allogeneic, pooled mesenchymal stromal cells for osteoarthritis of knee in a double-blind randomized placebo-controlled phase 3 study.Osteoarthritis and cartilage open · 2026Article
- Magnetic resonance fingerprinting for the whole knee articular cartilage assessment using automated pipeline.European radiology · 2026Article
- Comparative outcome analyses of stromal vascular fractionWorld journal of experimental medicine · 2025Article
- TJournal of magnetic resonance imaging : JMRI · 2025Article
- Comparison of test-retest repeatability of DESPOT and 3D-QALAS for TQuantitative imaging in medicine and surgery · 2025Article
- Beyond the Surface: Nutritional Interventions Integrated with Diagnostic Imaging Tools to Target and Preserve Cartilage Integrity: A Narrative Review.Biomedicines · 2025Review
- Unlocking the Mystery of Patella Dislocation-Diagnostic Methods in Pediatric Populations: A Comprehensive Narrative Review.Journal of clinical medicine · 2025Review
- In the Acute Phase of Anterior Cruciate Ligament Rupture: Quantitative Assessment of Matrix Changes and Correlation between Different States of Meniscus and Adjacent Cartilage.Orthopaedic surgery · 2024Article
- Influence of leg axis alignment on MRI T2* mapping of the knee in young professional soccer players.BMC musculoskeletal disorders · 2024Article
- Early patello-femoral condropathy assessment through quantitative analyses via T2 mapping magnetic resonance after anterior cruciate ligament reconstruction.La Radiologia medica · 2023Article
- Clinical Outcome of Minimally Manipulated, Mechanically Isolated Autologous Adipose Tissue-Derived Stromal Vascular Fraction (Sahaj Therapy®) in Knee Osteoarthritis-Randomized Controlled Trial.Indian journal of orthopaedics · 2023Article
- Insights into the Age Dependency of Compositional MR Biomarkers Quantifying the Health Status of Cartilage in Metacarpophalangeal Joints.Diagnostics (Basel, Switzerland) · 2023Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe aimed to analyze the distribution of knee cartilage degeneration in young patients with mild symptoms using quantitative magnetic resonance imaging (MRI) T2 mapping. MATERIALS AND
methodsThis study included sixty six patients (case group) and twenty eight healthy volunteers (control group). The participants underwent 3.0 T conventional MRI plus a multi-echo sequence. The cartilage of each participant was divided into twenty eight subregions. We then calculated the T2 mean values and standard deviation or median and quartile range for each subregion according to whether the normal distribution was satisfied. Besides, we employed Kruskal-Wallis test to determine the statistical differences of each subregion in the control group while the Mann-Whitney U test was used to define the statistical difference between the case group and the control group and between the control group and subjects aged less than or equal to 35 years in the case group.
resultsIn the case group, age of 30 male patients was 31.5 ± 9.3 and age of 36 female patients was 35.7 ± 8.3. In the two groups, the superficial central lateral femoral region exhibited relatively high T2 values (control/case group: 49.6 ± 2.7/55.9 ± 8.8), and the deep medial patellar region exhibited relatively low T2 values (control/case group: 34.2 ± 1.3/33.5(32.2, 35.5)). Comparison of the T2 values between the case and the control group demonstrated a statistically significant increase in nine subregions (P
conclusionT2 values of patients were significantly different with values of healthy groups, especially in the superficial cartilage of the patellofemoral joint. It made T2 mapping helpful to early identify patients with knee cartilage degeneration.
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