Evidence map›Paper›PMID 35436351›Full record

SynthesisScandinavian journal of psychology2022

Association between alexithymia and substance use: A systematic review and meta-analysis.

Kirsi Honkalampi, Markus Jokela, Soili M Lehto, Mika Kivimäki, Marianna Virtanen

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Scandinavian journal of psychology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
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  3. Temporal pathways between alexithymia, psychological distress, and pain: An autoregressive mediation analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 4 countries.

Kirsi HonkalampiSchool of Educational Sciences and Psychology, University of Eastern Finland, Joensuu, Finland.ORCID https://orcid.org/0000-0002-4328-5291
Markus JokelaDepartment of Psychology and Logopedics, University of Helsinki, Helsinki, Finland.ORCID https://orcid.org/0000-0003-0117-0012
Soili M LehtoDepartment of Psychology and Logopedics, University of Helsinki, Helsinki, Finland.ORCID https://orcid.org/0000-0003-4324-6679
Mika KivimäkiClinicum, Faculty of Medicine, University of Helsinki, Helsinki, Finland.ORCID https://orcid.org/0000-0002-4699-5627
Marianna VirtanenSchool of Educational Sciences and Psychology, University of Eastern Finland, Joensuu, Finland.ORCID https://orcid.org/0000-0001-8361-3301
University of Helsinki · FIUniversity of Eastern Finland · FI

Funding

Education, socioeconomic status and Aging: transitions from multimorbidity to functional limitations and mortalityR01AG056477 · NIA · UNIVERSITY COLLEGE LONDON · PI KIVIMAKI, MIKA J, SINGH-MANOUX, ARCHANA · 2018 to 2022
$2.8M
National Institute of Aging R01AG056477NIA NIH HHS R01 AG056477NordForsk 70521Terveyden Tutkimuksen Toimikunta 311492Työsuojelurahasto 190424UK Medical Research Council MRC S011676
6 · The paper itself

Abstract

Alexithymia has been associated with substance use, but the magnitude of the association has not been evaluated and sub-group differences, if any, are unknown. The aim of this meta-analysis is to systematically review the association between alexithymia and substance use (alcohol or illicit drugs). We identified studies through a systematic review of PubMed and Web of Science and obtained a total of 52 publications using the Toronto Alexithymia Scale-20 scale. Random effects meta-analysis was used to evaluate the overall and sub-group associations. Of the studies, 50 were cross-sectional and two longitudinal. Alexithymia was associated with any substance use (Cohen's d = 0.62, 95% confidence interval [CI] 0.49-0.76), with little difference between estimates for use of alcohol or illicit drugs. A stronger association was observed for the alexithymia dimension "Difficulty in Identifying Feelings" (d = 0.64, 95% CI = 0.47-0.81) and "Difficulty in Describing Feelings" (d = 0.44, 95% CI = 0.32-0.55) than for "Externally Oriented Thinking" (d = 0.19, 95% CI = 0.09-0.28). The association was stronger in studies with clinical patient populations (d = 0.83, 95% CI = 0.62-1.05) than in those investigating general or student populations, and in studies with a majority of male rather than female participants. These findings suggest a strong overall association between alexithymia and substance use and a very strong association among clinical patient populations. The association may be stronger with the emotion-related dimensions than with the cognition-related dimension of alexithymia. As nearly all the studies were cross-sectional, more longitudinal studies are needed.

Indexed as

Illicit DrugsSubstance-Related DisordersAffective SymptomsEmotionsFemaleHumansMaleStudentsIllicit DrugsalcoholAlexithymiadrinking behaviordrugsmeta-analysissubstance useTAS-20

Identifiers

PMID35436351
PMCPMC9790486
OpenAlexW4224227681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.