Evidence map›Paper›PMID 35435807›Full record

ArticleHuman vaccines & immunotherapeutics2022

Clinical characteristics, health care resource utilization and direct medical costs of Rotavirus hospitalizations in Spain (2013-2018).

Javier Arístegui, Santiago Alfayate-Miguelez, Begoña Carazo-Gallego, Elisa Garrote, Laura Díaz-Munilla, Mikel Mendizabal, María Méndez-Hernández, Elia Doménech, Belén Ferrer-Lorente, María Unsaín-Mancisidor and 8 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Human vaccines & immunotherapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 11 institutions in 1 country.

Javier ArísteguiPediatrics, Hospital Universitario de Basurto, Bilbao, Spain.
Santiago Alfayate-MiguelezPaediatrics, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain.
Begoña Carazo-GallegoPediatrics, Hospital Regional de Málaga, Málaga, Spain.
Elisa GarrotePediatrics, Hospital Universitario de Basurto, Bilbao, Spain.
Laura Díaz-MunillaPaediatrics, Complejo Hospitalario de Navarra, Pamplona, Spain.
Mikel MendizabalPaediatrics, Complejo Hospitalario de Navarra, Pamplona, Spain.
María Méndez-HernándezPaediatrics, Hospital Germans Trias i Pujol, Badalona, Spain.
Elia DoménechPaediatrics, Hospital Germans Trias i Pujol, Badalona, Spain.
Belén Ferrer-LorentePaediatrics, Hospital Germans Trias i Pujol, Badalona, Spain.
María Unsaín-MancisidorPaediatrics, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
José Tomás Ramos-AmadorPaediatrics, Hospital Universitario de Donostia, San Sebastián, Spain.
Marta Illán-RamosPaediatrics, Hospital Universitario de Donostia, San Sebastián, Spain.
Borja Croche-SantanderPaediatrics, Hospital Universitario Clínico San Carlos, Madrid, Spain.
Fernando Centeno MalfazPaediatrics, Hospital Juan Ramón Jiménez, Huelva, Spain.
Julián Rodríguez-SuárezPaediatrics, Hospital Universitario Río Hortega, Valladolid, Spain.
Manuel Cotarelo SuárezPaediatrics, Hospital Universitario Central de Asturias, Oviedo, Spain.
María San-MartínPaediatrics, Hospital Universitario Central de Asturias, Oviedo, Spain.
Jesús Ruiz-ContrerasMedical Affairs Department, MSD, Madrid, Spain.
Hospital Clínico San Carlos · ESComplejo Hospitalario de Navarra · ESHospital de Basurto · ESHospital Universitari Germans Trias i Pujol · ESHospital Universitario Central de Asturias · ESHospital Universitario Río Hortega · ESBiogipuzkoa Health Research Institute · ESHospital Regional Universitario de Málaga · ESHospital Universitari i Politècnic La Fe · ESHospital Universitario Virgen de la Arrixaca · ESMSD (Spain) · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rotavirus (RV) is the most common cause of severe gastroenteritis (GE) in infants and young children worldwide and is associated with a significant clinical and economic burden. The objective of this study was to analyze the characteristics, healthcare resource utilization and the direct medical costs related to RVGE hospitalizations in Spain. An observational, multicenter, cross-sectional study was conducted from June 2013 to May 2018 at the pediatric departments of 12 hospitals from different Spanish regions. Children under 5 years of age admitted to the hospital with a confirmed diagnosis of RVGE were selected. Data on clinical characteristics, healthcare resource use and costs were collected from patient records and hospital databases. Most children hospitalized for RVGE did not have any previous medical condition or chronic disease. Forty-seven percent had previously visited the Emergency Room (ER), 27% had visited a primary care pediatrician, and 15% had received pharmacological treatment prior to hospital admission due to an RVGE episode. The average length of a hospital stay for RVGE was 5.6 days, and the mean medical costs of RVGE hospitalizations per episode ranged from 3,940€ to 4,100€. The highest direct medical cost was due to the hospital stay. This study showed a high burden of health resource utilization and costs related to the management of cases of RVGE requiring hospitalization. RV vaccination with high coverage rates should be considered to minimize the clinical and economic impacts of this disease on the health-care system.

Indexed as

RotavirusRotavirus InfectionsRotavirus VaccinesChildChild, PreschoolCross-Sectional StudiesHospitalizationHumansInfantPatient Acceptance of Health CareSpainRotavirus Vaccinesacute gastroenteritisdirect costshealth care resourceshospitalizationRotavirusSpain

Identifiers

PMID35435807
PMCPMC9196715
OpenAlexW4226061040

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.