Evidence map›Paper›PMID 35435755›Full record

ArticleMicrobiology spectrum2022

Spermidine Is an Intercellular Signal Modulating T3SS Expression in Pseudomonas aeruginosa.

Qiqi Lin, Huishan Wang, Jiahui Huang, Zhiqing Liu, Qunyi Chen, Guohui Yu, Zeling Xu, Ping Cheng, Zhibin Liang, Lian-Hui Zhang

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. The Spermidine Synthase Gene as a Reporter of Transcription Inhibition inInternational journal of molecular sciences · 2026
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  5. The influence of the polyamine synthesis pathways onMicrobiology (Reading, England) · 2025
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  10. Suppression ofiScience · 2024
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  14. Article
  15. Discovering unknown associations between prokaryotic receptors and their ligands.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Qiqi Lin *Guangdong Province Key Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Center, South China Agricultural Universitygrid.20561.30, Guangzhou, China.
Huishan Wang *Guangdong Province Key Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Center, South China Agricultural Universitygrid.20561.30, Guangzhou, China.
Jiahui HuangGuangdong Province Key Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Center, South China Agricultural Universitygrid.20561.30, Guangzhou, China.
Zhiqing LiuGuangdong Province Key Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Center, South China Agricultural Universitygrid.20561.30, Guangzhou, China.
Qunyi ChenGuangdong Province Key Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Center, South China Agricultural Universitygrid.20561.30, Guangzhou, China.
Guohui YuInstitute of Plant Health, Zhongkai University of Agriculture and Engineeringgrid.449900.0, Guangzhou, China.
Zeling XuGuangdong Province Key Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Center, South China Agricultural Universitygrid.20561.30, Guangzhou, China.
Ping ChengInstitute of Plant Health, Zhongkai University of Agriculture and Engineeringgrid.449900.0, Guangzhou, China.
Zhibin LiangGuangdong Province Key Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Center, South China Agricultural Universitygrid.20561.30, Guangzhou, China.ORCID 0000-0003-3433-0975
Lian-Hui ZhangGuangdong Province Key Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Center, South China Agricultural Universitygrid.20561.30, Guangzhou, China.ORCID 0000-0002-4298-7988
South China Agricultural University · CNZhongkai University of Agriculture and Engineering · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pseudomonas aeruginosa is a vital opportunistic human bacterial pathogen that causes acute and chronic infections. In this study, we set to determine whether the endogenous spermidine biosynthesis plays a role in regulation of type III secretion system (T3SS). The results showed that deletion of

Indexed as

Pseudomonas aeruginosaSpermidineType III Secretion SystemsBacterial ProteinsGene Expression Regulation, BacterialPutrescineVirulence FactorsBacterial ProteinsPutrescineSpermidineType III Secretion SystemsVirulence FactorsexsCEBAquorum sensingregulationspermidineT3SS

Identifiers

PMID35435755
PMCPMC9241758
OpenAlexW4224119098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.