Evidence map›Paper›PMID 35435635›Full record

ArticleVirus genes2022

Molecular phylodynamics of infectious bursal disease viruses.

Aditya A Agnihotri, Sudhakar P Awandkar, Mahesh B Kulkarni, Sambhaji G Chavhan, Ram C Kulkarni, Vishranti G Chavan

Abstract read
PubMed Publisher
In one paragraph

Article in Virus genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aditya A AgnihotriDepartment of Veterinary Microbiology, College of Veterinary & Animal Sciences, Maharashtra Animal & Fishery Sciences University, Udgir, Maharashtra, India.
Sudhakar P AwandkarDepartment of Veterinary Microbiology, College of Veterinary & Animal Sciences, Maharashtra Animal & Fishery Sciences University, Udgir, Maharashtra, India. drspawandkar@gmail.com.ORCID http://orcid.org/0000-0002-7171-8576
Mahesh B KulkarniDepartment of Veterinary Microbiology, College of Veterinary & Animal Sciences, Maharashtra Animal & Fishery Sciences University, Udgir, Maharashtra, India.
Sambhaji G ChavhanDepartment of Veterinary Pathology, College of Veterinary & Animal Sciences, Maharashtra Animal & Fishery Sciences University, Udgir, Maharashtra, India.
Ram C KulkarniDepartment of Poultry Science, College of Veterinary & Animal Sciences, Maharashtra Animal & Fishery Sciences University, Udgir, Maharashtra, India.
Vishranti G ChavanDepartment of Veterinary Microbiology, College of Veterinary & Animal Sciences, Maharashtra Animal & Fishery Sciences University, Udgir, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study was conducted to study the molecular phylodynamics of the Indian field IBDVs. A total of 13 organized commercial poultry farms and 29 village poultry flocks were recruited in the study. The broiler flocks showed 15.25-60.18% mortality, followed by 12.4% in improved native poultry varieties and 5% in indigenous birds. The 664 bp hypervariable VP2 gene fragment of Western and Central Indian vvIBDVs showed 97.14-98.79 and 94.49-96.69% identity to Pakistani and South Indian vvIBDVs, respectively. An isolate was 99.54% identical to the Ventri-Plus vaccine strain, while three IBDVs showed maximum identity with the Georgia strain. Out of 22, 19 strains showed typical vvIBDV amino acid signature, while three strains showed substitutions specific to classical IBDVs. Central Indian vvIBDVs showed conserved substitutions at N212D and E300A, which can be used as a regional marker. Phylogenetic genogrouping placed global IBDVs into seven genogroups based upon virulence and geographical distribution. Nineteen field vvIBDVs were placed in the G3 genogroup, and the other three were grouped with classical IBDVs in G1 genogroup. A nucleotide span from 584 to 1248 covering VP2 hypervariable fragment was found suitable for correct genogrouping of field IBDVs. The Bayesian evolutionary analysis showed tMRCA of the year 2009 for 8 Western Indian vvIBDVs with vvIBDV from Pakistan. Central Indian vvIBDVs were evolved in the year 1991 from BD-3 and PY12 strains of vvIBDVs from Bangladesh and Pondicherry, respectively. An isolate showed evolution in year 2010 from the Nigerian ABIC strain, while three classical strains showed tMRCA of the year 2009 with the Georgia strain as a recent common ancestor.

Indexed as

Birnaviridae InfectionsInfectious bursal disease virusPoultry DiseasesAmino Acid SequenceAnimalsBayes TheoremChickensPhylogenyViral Structural ProteinsViral Structural ProteinsEvolutionGenogroupsIBDVtMRCA

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.