Evidence map›Paper›PMID 35435502›Full record

ArticleEuropean journal of nutrition2022

Moderate adiposity levels counteract protein metabolism modifications associated with aging in rats.

Nathalie Atallah, Claire Gaudichon, Audrey Boulier, Alain Baniel, Dalila Azzout-Marniche, Nadezda Khodorova, Catherine Chaumontet, Julien Piedcoq, Martin Chapelais, Juliane Calvez

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in European journal of nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Nathalie AtallahUniversité Paris-Saclay, AgroParisTech, INRAE, UMR PNCA, 75005, Paris, France.
Claire GaudichonUniversité Paris-Saclay, AgroParisTech, INRAE, UMR PNCA, 75005, Paris, France.
Audrey BoulierIngredia S.A., 62033, Arras Cedex, France.
Alain BanielIngredia S.A., 62033, Arras Cedex, France.
Dalila Azzout-MarnicheUniversité Paris-Saclay, AgroParisTech, INRAE, UMR PNCA, 75005, Paris, France.
Nadezda KhodorovaUniversité Paris-Saclay, AgroParisTech, INRAE, UMR PNCA, 75005, Paris, France.
Catherine ChaumontetUniversité Paris-Saclay, AgroParisTech, INRAE, UMR PNCA, 75005, Paris, France.
Julien PiedcoqUniversité Paris-Saclay, AgroParisTech, INRAE, UMR PNCA, 75005, Paris, France.
Martin ChapelaisUniversité Paris-Saclay, AgroParisTech, INRAE, UMR PNCA, 75005, Paris, France.
Juliane CalvezUniversité Paris-Saclay, AgroParisTech, INRAE, UMR PNCA, 75005, Paris, France. juliane.calvez@agroparistech.fr.ORCID http://orcid.org/0000-0003-1181-9786
AgroParisTech · FRIngredia (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePhysiological parameters such as adiposity and age are likely to influence protein digestion and utilization. The aim of this study was to evaluate the combined effects of age and adiposity on casein protein and amino acid true digestibility and its postprandial utilization in rats.

methodsFour groups were included (n = 7/8): 2 months/normal adiposity, 2 months/high adiposity, 11 months/normal adiposity and 11 months/high adiposity. Rats were given a calibrated meal containing

resultsNitrogen and amino acid true digestibility of casein was around 95-96% depending on the group and was increased by 1% in high adiposity rats (P = 0.04). Higher adiposity levels counteracted the increase in total body deamination (P = 0.03) that was associated with older age. Significant effects of age (P = 0.006) and adiposity (P = 0.002) were observed in the muscle FSR, with age decreasing it and adiposity increasing it.

conclusionThis study revealed that a higher level of adiposity resulted in a slight increase in protein and individual amino acid true digestibility values and seemed to compensate for the metabolic postprandial protein alterations observed at older age.

Indexed as

CaseinsIleumAdiposityAgingAmino AcidsAnimalsDietary ProteinsDigestionRatsAmino AcidsCaseinsDietary ProteinsAgingAmino acid digestibilityObesityProtein metabolismRat model

Identifiers

PMID35435502
OpenAlexW4224042683

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.