Evidence map›Paper›PMID 35435445›Full record

ArticleRheumatology international2022

Patient characteristics, treatment patterns and disease outcomes in patients with psoriatic arthritis followed in a combined Dermatology-Rheumatology clinic: a retrospective real-world study.

Kalliopi Klavdianou, Maria Stavropoulou, Pantelis Panagakis, Marina Papoutsaki, Alexandros Panagiotopoulos, Christos Koutsianas, Alexandros Stratigos, Dimitrios Rigopoulos, Dimitrios Vassilopoulos

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Article in Rheumatology international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Kalliopi KlavdianouSchool of Medicine, 2nd Department of Medicine and Laboratory, Clinical Immunology-Rheumatology Unit, National and Kapodistrian University of Athens, Hippokration General Hospital, 114 Vass. Sophias Ave., 115 27, Athens, Greece.ORCID 0000-0002-1267-1106
Maria StavropoulouSchool of Medicine, MSc Program "Rheumatology-Musculoskeletal Health", School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.ORCID 0000-0002-0792-1203
Pantelis PanagakisDepartment of Dermatology-Venereology, National Health System, A. Sygros Hospital, Athens, Greece.
Marina PapoutsakiSchool of Medicine, 1st Department of Dermatology and Venereology, A. Sygros Hospital, National and Kapodistrian University of Athens, Athens, Greece.ORCID 0000-0002-2422-0994
Alexandros PanagiotopoulosSchool of Medicine, 2nd Department of Medicine and Laboratory, Clinical Immunology-Rheumatology Unit, National and Kapodistrian University of Athens, Hippokration General Hospital, 114 Vass. Sophias Ave., 115 27, Athens, Greece.ORCID 0000-0003-3612-9394
Christos KoutsianasSchool of Medicine, 2nd Department of Medicine and Laboratory, Clinical Immunology-Rheumatology Unit, National and Kapodistrian University of Athens, Hippokration General Hospital, 114 Vass. Sophias Ave., 115 27, Athens, Greece.ORCID 0000-0002-6621-6918
Alexandros StratigosSchool of Medicine, 1st Department of Dermatology and Venereology, A. Sygros Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Dimitrios RigopoulosSchool of Medicine, 1st Department of Dermatology and Venereology, A. Sygros Hospital, National and Kapodistrian University of Athens, Athens, Greece.ORCID 0000-0002-4841-7484
Dimitrios VassilopoulosSchool of Medicine, 2nd Department of Medicine and Laboratory, Clinical Immunology-Rheumatology Unit, National and Kapodistrian University of Athens, Hippokration General Hospital, 114 Vass. Sophias Ave., 115 27, Athens, Greece. dvassilop@med.uoa.gr.ORCID 0000-0003-2288-3863
National and Kapodistrian University of Athens · GRAndreas Sygros Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to assess the patient characteristics, treatment patterns and disease outcomes in patients with psoriatic arthritis (PsA) referred to a combined Dermatology-Rheumatology (Derm-Rheum) Clinic. This was a retrospective study of patients seen in a combined Derm-Rheum Clinic (February 2018 to June 2020) in a Tertiary University Hospital. Consecutive patients with suspicious musculoskeletal symptoms or a known diagnosis of PsA referred to the Derm-Rheum Clinic were examined and followed simultaneously by experienced dermatologists and rheumatologists. Among 151 patients with psoriasis (PSO) with suspicious musculoskeletal complaints, 129 (85%) with a final diagnosis of PsA were included (56% females, mean age: 55 years, median disease duration: 14.2 years). In 62% of these patients (n = 94), PsA was diagnosed for the 1st time. At initial evaluation, 95% had peripheral arthritis, 45% nail involvement, 23% axial involvement, 12% enthesitis and 6% dactylitis with a median DAPSA and PASI scores of 20.5 and 1.6, respectively. 31% of the patients were not receiving any systemic treatment, 45% were on biologics, 29% on non-biologics and 10% on targeted synthetic agents (apremilast). At last visit (median interval time: 15 months), only 8% did not receive any systemic therapy (p < 0.001 compared to 1st visit), 62% were on biologics (p = 0.009 compared to 1st visit), 46% on non-biologics (p = 0.01 compared to 1st visit) and 10% remained on apremilast. The median DAPSA and PASI scores decreased significantly to 5.3 and 0, respectively. In conclusion, about 2/3 of patients with PSO and musculoskeletal complaints referred to a combined Derm-Rheum Clinic were diagnosed for the 1st time with PsA. During follow-up, the percentage of PsA patients on systemic therapies significantly increased with major improvement of disease activity indices. These data emphasize the value of combined Derm-Rheum Clinics for earlier referral, diagnosis, and more effective treatment of PsA patients.

Indexed as

Arthritis, PsoriaticBiological ProductsDermatologyPsoriasisRheumatologyFemaleHumansMaleMiddle AgedRetrospective StudiesBiological ProductsInterdisciplinary health teamPsoriasisPsoriatic arthritisSpondyloarthritis

Identifiers

PMID35435445
OpenAlexW4224137329

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.