Evidence map›Paper›PMID 35435152›Full record

ArticleOrganogenesis2022

Hepatocyte Differentiation from iPSCs or MSCs in Decellularized Liver Scaffold: Cell-ECM Adhesion, Spatial Distribution, and Hepatocyte Maturation Profile.

Radiana Dhewayani Antarianto, Adrian Pragiwaksana, Wahyunia Likhayati Septiana, Nuzli Fahdia Mazfufah, Ameer Mahmood

Open access · diamondAbstract read
In one paragraph

Article in Organogenesis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. A CYP3A7 metabolically competent human induced pluripotent stem cell-derived hepatocyte-like cell (hHLCDrug metabolism and disposition: the biological fate of chemicals · 2026
    Article
  2. Article
  3. Review
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  5. Article
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  8. iPSC-derived cells for whole liver bioengineering.Frontiers in bioengineering and biotechnology · 2024
    Review
  9. Article
  10. Stem cell therapy for hepatocellular carcinoma and end-stage liver disease.Journal of the Egyptian National Cancer Institute · 2023
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Suppressive effect of pseudolaric acid B onFrontiers in microbiology · 2022
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Radiana Dhewayani AntariantoDepartment of Histology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.ORCID 0000-0002-8578-7505
Adrian PragiwaksanaProgram Master Ilmu Biomedik, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Wahyunia Likhayati SeptianaProgram Doktor Ilmu Biomedik, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Nuzli Fahdia MazfufahStem cell and tissue engineering research cluster, (IMERI) Indonesian Medical Education and Research Institute, Jakarta Indonesia.
Ameer MahmoodStem cell unit Department of Anatomy, King Saud University, Riyadh, Kingdom Saudi Arabia.
University of Indonesia · IDKing Saud University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stem cells (MSC) and induced pluripotent stem cells (iPSC) have been reported to be able to differentiate to hepatocyte in vitro with varying degree of hepatocyte maturation. A simple method to decellularize liver scaffold has been established by the Department of Histology, Faculty of Medicine, Universitas Indonesia, in SCTE IMERI lab.

Indexed as

Induced Pluripotent Stem CellsAlbuminsCell DifferentiationHepatocytesLiverTissue ScaffoldsAlbuminsdecellularized-liver-scaffolddifferentiationHepatocyteiPSCsMSCs

Identifiers

PMID35435152
PMCPMC9037523
OpenAlexW4224212982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.