Evidence map›Paper›PMID 35434991›Full record

ReviewEnvironmental science & technology2022

Waterborne Human Pathogenic Viruses in Complex Microbial Communities: Environmental Implication on Virus Infectivity, Persistence, and Disinfection.

Mengyang Zhang, Nihal Altan-Bonnet, Yun Shen, Danmeng Shuai

Open access · greenAbstract readReview
In one paragraph

Review in Environmental science & technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
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  3. Review
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  8. Diversity of lake bacteria promotes human echovirus inactivation.Applied and environmental microbiology · 2025
    Article
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  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Mengyang ZhangDepartment of Civil and Environmental Engineering, The George Washington University, Washington, D.C. 20052, United States.
Nihal Altan-BonnetLaboratory of Host-Pathogen Dynamics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, United States.
Yun ShenDepartment of Chemical and Environmental Engineering, University of California, Riverside, Riverside, California 92521, United States.ORCID 0000-0002-8225-1940
Danmeng ShuaiDepartment of Civil and Environmental Engineering, The George Washington University, Washington, D.C. 20052, United States.ORCID 0000-0003-3817-4092
National Institutes of Health · USGeorge Washington University · USUniversity of California, Riverside · US

Funding

Virus Egress PathwaysZIAHL006234 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI ALTAN-BONNET, NIHAL · 2017 to 2025
$21.8M
Vesicle-Cloaked Virus Clusters as Emerging Pathogens: Will They Challenge Current Disinfection Paradigm?R21AI154049 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI SHEN, YUN, SHUAI, DANMENG · 2021 to 2022
$490k
NIAID NIH HHS R21 AI154049
6 · The paper itself

Abstract

Waterborne human pathogenic viruses challenge global health and economy. Viruses were long believed to transmit among hosts as individual, free particles. However, recent evidence indicates that viruses also transmit in populations, so-called en bloc transmission, by either interacting with coexisting bacteria, free-living amoebas, and other higher organisms through endosymbiosis and surface binding, or by being clustered inside membrane-bound vesicles or simply self-aggregating with themselves. En bloc transmission of viruses and virus-microbiome interactions could enable viruses to enhance their infectivity, increase environmental persistence, and resist inactivation from disinfection. Overlooking this type of transmission and virus-microbiome interactions may underestimate the environmental and public health risks of the viruses. We herein provide a critical perspective on waterborne human pathogenic viruses in complex microbial communities to elucidate the environmental implication of virus-microbiome interactions on virus infectivity, persistence, and disinfection. This perspective also provides insights on advancing disinfection and sanitation guidelines and regulations to protect the public health.

Indexed as

MicrobiotaVirusesBacteriaDisinfectionHumansamoebabacteriadisinfectionenvironmental persistencevesicle-cloaked virus clusterswaterborne human pathogenic virus

Identifiers

PMID35434991
PMCPMC9073700
OpenAlexW4224028592

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.