Evidence map›Paper›PMID 35434964›Full record

ArticleOrthopaedic surgery2022

Avoiding Misdiagnosis and Missed Diagnosis for Appropriately Treating Spinal Osteoid Osteomas: A Single-Center Experience.

Qiming Xu, Wensheng Liu, Hairong Xu, Lijia Cui, Yuan Li, Huachao Shan, Zhen Huang, Ke Ma, Xiaohui Niu

Open access · goldAbstract read
In one paragraph

Article in Orthopaedic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Qiming XuDepartment of Orthopaedic Oncology, Beijing Jishuitan Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-0498-1323
Wensheng LiuDepartment of Orthopaedic Oncology, Beijing Jishuitan Hospital, Beijing, China.
Hairong XuDepartment of Orthopaedic Oncology, Beijing Jishuitan Hospital, Beijing, China.
Lijia CuiDepartment of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Key Laboratory of Endocrinology, National Health Commission, Beijing, China.
Yuan LiDepartment of Orthopaedic Oncology, Beijing Jishuitan Hospital, Beijing, China.
Huachao ShanDepartment of Orthopaedic Oncology, Beijing Jishuitan Hospital, Beijing, China.
Zhen HuangDepartment of Orthopaedic Oncology, Beijing Jishuitan Hospital, Beijing, China.
Ke MaDepartment of Orthopaedic Oncology, Beijing Jishuitan Hospital, Beijing, China.
Xiaohui NiuDepartment of Orthopaedic Oncology, Beijing Jishuitan Hospital, Beijing, China.
Peking University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

Beijing JST Research Funding ZR-201903Bethune Charitable Foundation G-X-2020-1107-16National Key R&D Program of China (XN, 2021YFC2400500)National Natural Science Foundation of China 82100946Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences 2017PT32020Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences 2018PT32001
6 · The paper itself

Abstract

objectivesTo analyze the causes of misdiagnosis and missed diagnosis in spinal osteoid osteoma, and to put forward solutions to improve diagnosis accuracy and treatment efficacy in patients.

methodsWe performed a retrospective cohort study on patients with spinal osteoid osteoma in Beijing Jishuitan Hospital from January 1983 to September 2019. All patients underwent surgery. The outcome measures were the extent of local pain, nocturnal pain, radicular symptoms of extremities after surgery, and reduction or disappearance of lesions on CT after surgery.

resultsThirty-seven patients with spinal osteoid osteoma were recruited in the study. A total of 27% were female, and the mean (SD) age at diagnosis was 21.3 (8.7) years. A total of 87.0% of patients presented with nocturnal pain, and 94.7% of patients were responsive to NSAIDS treatment. The mean (SD) time from the initial onset of symptoms to the final diagnosis was 14.7 (12.5) months. Only four of 37 (10.8%) patients were correctly diagnosed with spinal osteoid osteoma on the first visit to the local hospital. CT is associated with a higher diagnosis rate than X-ray or MRI on the first visit. Surgical navigation was used in 88.9% of patients who underwent curettage resection, and in 10% of patients who underwent en bloc resection. A total of 37 of 37 patients (100%) reported relief of local pain and radicular symptoms of extremities after surgery, and no recurrence of tumors was found during follow-ups.

conclusionsSpinal CTs are recommended to be performed if osteoid osteoma is suspected based on clinical manifestation, including nocturnal pain and responsiveness to NSAIDS treatment, to avoid misdiagnosis and missed diagnosis of spinal osteoid osteoma.

Indexed as

Bone NeoplasmsOsteoma, OsteoidSpinal NeoplasmsAnti-Inflammatory Agents, Non-SteroidalDiagnostic ErrorsFemaleHumansMaleMissed DiagnosisPainRetrospective StudiesAnti-Inflammatory Agents, Non-SteroidalMisdiagnosisMissed diagnosisOsteoid osteomaSpineSurgery

Identifiers

PMID35434964
PMCPMC9087446
OpenAlexW4223909775

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.