Evidence map›Paper›PMID 35434937›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2022

Hierarchy-Assembled Dual Probiotics System Ameliorates Cholestatic Drug-Induced Liver Injury via Gut-Liver Axis Modulation.

Qi-Wen Chen, Qian-Ru Li, Meng-Wei Cao, Jian-Hua Yan, Xian-Zheng Zhang

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
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  6. Antioxidants (Basel, Switzerland) · 2025
    Article
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  9. Article
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  13. The Roles of Myeloid Cells in Aging-related Liver Diseases.International journal of biological sciences · 2023
    Review
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  15. Article
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Qi-Wen ChenKey Laboratory of Biomedical Polymers of Ministry of Education and Department of Chemistry, Wuhan University, Wuhan, 430072, P. R. China.
Qian-Ru LiKey Laboratory of Biomedical Polymers of Ministry of Education and Department of Chemistry, Wuhan University, Wuhan, 430072, P. R. China.
Meng-Wei CaoKey Laboratory of Biomedical Polymers of Ministry of Education and Department of Chemistry, Wuhan University, Wuhan, 430072, P. R. China.
Jian-Hua YanKey Laboratory of Biomedical Polymers of Ministry of Education and Department of Chemistry, Wuhan University, Wuhan, 430072, P. R. China.
Xian-Zheng ZhangKey Laboratory of Biomedical Polymers of Ministry of Education and Department of Chemistry, Wuhan University, Wuhan, 430072, P. R. China.ORCID 0000-0001-6242-6005
Wuhan University · CN

Funding

China Postdoctoral Science Foundation 2021TQ0250IACUC of the Animal Experiment Center of Wuhan University WP20210443National Key Research and Development Program of China 2019YFA0905603National Natural Science Foundation of China 22135005National Natural Science Foundation of China 51833007National Natural Science Foundation of China 52131302Postdoctoral Research Foundation of China 2021TQ0250
6 · The paper itself

Abstract

Cholestatic drug-induced liver injury (DILI) induced by drugs or other xenobiotics is a severe and even fatal clinical syndrome. Here, living materials of hierarchy-assembled dual probiotics system are fabricated by sequentially encapsulating probiotic Lactobacillus delbrueckii subsp. bulgaricus (LDB) and Lactobacillus rhamnosus GG (LGG) into Ca

Indexed as

Chemical and Drug Induced Liver InjuryCholestasisProbioticsAnimalsFibroblast Growth FactorsMicePolymersFibroblast Growth FactorsPolymerscholestasisintestinal tractliver injurypolymer microsphereprobiotics

Identifiers

PMID35434937
PMCPMC9189648
OpenAlexW4223929556

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.