ArticleJournal of neuroscience research2022
Childhood trauma exposure and reward processing in healthy adults: A functional neuroimaging study.
Article in Journal of neuroscience research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- How childhood adversity affects components of decision making.Neuroscience and biobehavioral reviews · 2025Pooled it
- Pooled it
- Distinct neural responses to punishment anticipation in violent and non-violent individuals with schizophrenia.European archives of psychiatry and clinical neuroscience · 2026Article
- Sex-specific associations of childhood adversity with frontostriatal network organization and anhedonia in young adulthood.bioRxiv : the preprint server for biology · 2026Article
- Cognitive and affective neurodevelopment in youth exposed to deprivation and threat.bioRxiv : the preprint server for biology · 2026Article
- Associations between birth-related stressors, social reward responsiveness, and postpartum internalizing symptoms.Anxiety, stress, and coping · 2026Article
- Differential associations of childhood abuse and neglect with neural responses to social reward and punishment in adults with anxiety or depression.Translational psychiatry · 2026Article
- Reimagining the biopsychosocial model: hierarchical mechanisms from transdiagnostic to precision psychiatry.Journal of psychiatry & neuroscience : JPN · 2026Review
- Differential Associations of Childhood Abuse and Neglect with Neural Responses to Social Reward and Punishment in Adults with Anxiety or Depression.Research square · 2025Article
- Effects of Early Adversity and War Trauma on Learning Under Uncertainty.Developmental science · 2025Article
- Trauma and anxiety interactions relate to reward processing in adolescents.Journal of affective disorders · 2025Article
- Increased Brain Age Among Psychiatrically Healthy Adults Exposed to Childhood Trauma.Brain and behavior · 2025Article
- Common and distinct neural underpinnings of the association between childhood maltreatment and depression and aggressive behavior.BMC psychiatry · 2025Article
- Severe sexual abuse in childhood and altered neurophysiological response to reward in female adults.Child abuse & neglect · 2024Article
- Exposure to community violence as a mechanism linking neighborhood socioeconomic disadvantage and neural responses to reward.Social cognitive and affective neuroscience · 2024Article
- The Stress Phenotyping Framework: A multidisciplinary biobehavioral approach for assessing and therapeutically targeting maladaptive stress physiology.Stress (Amsterdam, Netherlands) · 2024Review
- Developmental Changes in Habenular and Striatal Social Reinforcement Responsivity Across Adolescence Linked With Substance Use.Biological psychiatry · 2023Article
- The involvement of spontaneous brain activity in natural recovery from internet gaming disorder: A resting-state fMRI study.Frontiers in psychiatry · 2023Article
- Childhood trauma exposure and reward processing in healthy adults: A functional neuroimaging study.Journal of neuroscience research · 2022Article
- Acute and Lifetime Stress and Psychotic Illness: The Roles of Reward and Salience Networks.Journal of psychiatry and brain science · 2022Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The association between childhood trauma exposure and risk of developing psychopathology may in part be mediated by the effects of chronic stress on dopaminergic neurotransmission. However, little is known about the differential effects of distinct trauma types on reward processing, particularly in adults without concurrent medical or psychiatric disorders. We examined the association of childhood trauma exposure, including the differential effects of abuse and neglect, with reward processing in healthy adults (n = 114). Functional magnetic resonance imaging during a monetary incentive delay task was used to assess neural activity in the ventral striatum and orbitofrontal cortex in relation to reward anticipation and reward outcome, respectively. Exposure to childhood trauma, including abuse and neglect, was assessed using the Childhood Trauma Questionnaire-Short Form. We found a significant effect for abuse on ventral striatal activation during reward anticipation, adjusting for age, sex, scanner site, educational level, and household monthly income. There were no effects for abuse or neglect, independently or combined, on orbitofrontal cortex activation during reward outcome. Our findings suggest differential effects of childhood abuse on ventral striatum activation during reward anticipation in healthy adults.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.