ArticleCurrent research in physiology2022
Shaping the cardiac response to hypoxia: NO and its partners in teleost fish.
Article in Current research in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- The impact of adult and lifelong hypoxia on ventricle phenotype in zebrafish (American journal of physiology. Regulatory, integrative and comparative physiology · 2025Article
- Development and sex affect respiratory responses to temperature and dissolved oxygen in the air-breathing fishes Betta splendens and Trichopodus trichopterus.Fish physiology and biochemistry · 2025Article
- The cardiac response of the goldfish Carassius auratus to environmental hypoxia: from hemodynamics to mitochondria.Fish physiology and biochemistry · 2025Article
- Functional, structural, and molecular remodelling of the goldfish (Carassius auratus) heart under moderate hypoxia.Fish physiology and biochemistry · 2024Article
- Nitric Oxide Function and Nitric Oxide Synthase Evolution in Aquatic Chordates.International journal of molecular sciences · 2023Review
- Cardiac Hypoxia Tolerance in Fish: From Functional Responses to Cell Signals.International journal of molecular sciences · 2023Review
- An ACE2-Alamandine Axis Modulates the Cardiac Performance of the GoldfishAntioxidants (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The reduced availability of dissolved oxygen is a common stressor in aquatic habitats that affects the ability of the heart to ensure tissue oxygen supply. Among key signalling molecules activated during cardiac hypoxic stress, nitric oxide (NO) has emerged as a central player involved in the related adaptive responses. Here, we outline the role of the nitrergic control in modulating tolerance and adaptation of teleost heart to hypoxia, as well as major molecular players that participate in the complex NO network. The purpose is to provide a framework in which to depict how the heart deals with limitations in oxygen supply. In this perspective, defining the relational interplay between the multiple (sets of) proteins that, due to the gene duplication events that occurred during the teleost fish evolutive radiation, do operate in parallel with similar functions in the (different) heart (districts) and other body districts under low levels of oxygen supply, represents a next goal of the comparative research in teleost fish cardiac physiology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.