Evidence map›Paper›PMID 35434629›Full record

ReviewRSC medicinal chemistry2022

Bifunctional chelators for radiorhenium: past, present and future outlook.

Diana R Melis, Andrew R Burgoyne, Maarten Ooms, Gilles Gasser

Open access · greenAbstract readReview
In one paragraph

Review in RSC medicinal chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Chelator Optimization and Therapeutic Potential ofACS medicinal chemistry letters · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Diana R MelisSCK CEN, Belgian Nuclear Research Centre Boeretang 200 BE-2400 Mol Belgium andrew.burgoyne@sckcen.be maarten.ooms@sckcen.be +1 865 341 1413 +32 14 33 32 83.ORCID https://orcid.org/0000-0001-5415-4484
Andrew R BurgoyneSCK CEN, Belgian Nuclear Research Centre Boeretang 200 BE-2400 Mol Belgium andrew.burgoyne@sckcen.be maarten.ooms@sckcen.be +1 865 341 1413 +32 14 33 32 83.ORCID https://orcid.org/0000-0002-9342-4245
Maarten OomsSCK CEN, Belgian Nuclear Research Centre Boeretang 200 BE-2400 Mol Belgium andrew.burgoyne@sckcen.be maarten.ooms@sckcen.be +1 865 341 1413 +32 14 33 32 83.ORCID https://orcid.org/0000-0002-7489-1630
Gilles GasserChimie ParisTech, Laboratory for Inorganic Chemical Biology, PSL University F-75005 Paris France gilles.gasser@chimieparistech.psl.eu www.gassergroup.com +33 1 44 27 56 02.ORCID https://orcid.org/0000-0002-4244-5097
Belgian Nuclear Research Centre · BEChimie ParisTech · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Targeted radionuclide therapy (TRNT) is an ever-expanding field of nuclear medicine that provides a personalised approach to cancer treatment while limiting toxicity to normal tissues. It involves the radiolabelling of a biological targeting vector with an appropriate therapeutic radionuclide, often facilitated by the use of a bifunctional chelator (BFC) to stably link the two entities. The radioisotopes of rhenium,

Identifiers

PMID35434629
PMCPMC8942221
OpenAlexW4205521627

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.