Evidence map›Paper›PMID 35434542›Full record

ArticleiScience2022

The value of longitudinal clinical data and paired CT scans in predicting the deterioration of COVID-19 revealed by an artificial intelligence system.

Xiaoyang Han, Ziqi Yu, Yaoyao Zhuo, Botao Zhao, Yan Ren, Lorenz Lamm, Xiangyang Xue, Jianfeng Feng, Carsten Marr, Fei Shan and 2 more

Abstract read
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. MVASA-HGN: multi-view adaptive semantic-aware heterogeneous graph network forQuantitative imaging in medicine and surgery · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xiaoyang HanInstitute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai 200433, China.
Ziqi YuInstitute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai 200433, China.
Yaoyao ZhuoDepartment of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Botao ZhaoInstitute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai 200433, China.
Yan RenDepartment of Radiology, Huashan Hospital, Fudan University, Shanghai 200433, China.
Lorenz LammInstitute of AI for Health, Helmholtz Zentrum München, Ingolstädter Landstraße 1, D-85764 Neuherberg, Germany.
Xiangyang XueShanghai Key Laboratory of Intelligent Information Processing, School of Computer Science, Fudan University, Shanghai 200433, China.
Jianfeng FengInstitute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai 200433, China.
Carsten MarrInstitute of AI for Health, Helmholtz Zentrum München, Ingolstädter Landstraße 1, D-85764 Neuherberg, Germany.
Fei ShanDepartment of Radiology, Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China.
Tingying PengHelmholtz AI, Helmholtz Zentrum München, Ingolstädter Landstraße 1, D-85764 Neuherberg, Germany.
Xiao-Yong ZhangInstitute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai 200433, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The respective value of clinical data and CT examinations in predicting COVID-19 progression is unclear, because the CT scans and clinical data previously used are not synchronized in time. To address this issue, we collected 119 COVID-19 patients with 341 longitudinal CT scans and paired clinical data, and we developed an AI system for the prediction of COVID-19 deterioration. By combining features extracted from CT and clinical data with our system, we can predict whether a patient will develop severe symptoms during hospitalization. Complementary to clinical data, CT examinations show significant add-on values for the prediction of COVID-19 progression in the early stage of COVID-19, especially in the 6

Indexed as

artificial intelligencehealth sciencesmachine learningmicrobiology

Identifiers

PMID35434542
PMCPMC8989658

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.