ArticleEnvironmental epidemiology (Philadelphia, Pa.)2022
Applying the exposome concept to working life health: The EU EPHOR project.
Article in Environmental epidemiology (Philadelphia, Pa.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Cohort Profile: The European Occupational Exposome Mega Cohort Consortium (OMega-X).International journal of epidemiology · 2026Article
- The Epidemiology of Working Life: Reorganizing Occupational Health Science Around Work-Structured Exposure Systems.American journal of industrial medicine · 2026Article
- Polycyclic aromatic hydrocarbon exposure in battlefield and beyond: Implications for environmental- and human health.Toxicology reports · 2026Review
- Development of a European job exposure matrix (EuroJEM) for psychosocial exposures and their association with diagnosed depression in register-based cohorts.Scandinavian journal of work, environment & health · 2026Article
- One Health perspective on mycotoxins in poultry production: Ecology, toxicological effects, occupational and environmental exposure, food safety risks, and mitigation strategies (2020-2025).Veterinary world · 2026Review
- Translating multi-omics into healthcare: requisites for scalable and equitable implementation.Human genomics · 2026Review
- Article
- Advancing translational exposomics: bridging genome, exposome and personalized medicine.Human genomics · 2025Review
- Global research trends on the human exposome: a bibliometric analysis (2005-2024).Environmental science and pollution research international · 2025Review
- Development of a gender-specific European job exposure matrix (EuroJEM) for physical workload and its validation against musculoskeletal pain.Scandinavian journal of work, environment & health · 2025Article
- Genomics and multiomics in the age of precision medicine.Pediatric research · 2025Review
- Cohort Profile: The Nor-Work Cohort.International journal of epidemiology · 2025Article
- Rethinking the rise of early-onset gastrointestinal cancers: a call to action.JNCI cancer spectrum · 2025Article
- Occupational exposure and its mechanistic link to allergic asthma and lung function decline; a data-driven approach coupled to mining of adverse outcome pathway signatures.Frontiers in toxicology · 2025Article
- Five decades of occupational cancer epidemiology.Scandinavian journal of work, environment & health · 2024Review
- Worker perspectives on improving occupational health and safety using wearable sensors: a cross-sectional survey.Annals of work exposures and health · 2024Article
- Reconceptualizing and Defining Exposomics within Environmental Health: Expanding the Scope of Health Research.Environmental health perspectives · 2024Article
- Narrative review of occupational exposures and noncommunicable diseases.Annals of work exposures and health · 2024Review
- Integrating a life course perspective in work environment and health research: empirical challenges and interdisciplinary opportunities.Scandinavian journal of work, environment & health · 2024Article
- Decoding depression by exploring the exposome-genome edge amidst COVID-19 lockdown.Scientific reports · 2024Article
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Authors and funding
20 authors.
Funding
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Abstract
Exposures at work have a major impact on noncommunicable diseases (NCDs). Current risk reduction policies and strategies are informed by existing scientific evidence, which is limited due to the challenges of studying the complex relationship between exposure at work and outside work and health. We define the working life exposome as all occupational and related nonoccupational exposures. The latter includes nonoccupational exposures that may be directly or indirectly influenced by or interact with the working life of the individual in their relation to health. The Exposome Project for Health and Occupational Research aims to advance knowledge on the complex working life exposures in relation to disease beyond the single high exposure-single health outcome paradigm, mapping and relating interrelated exposures to inherent biological pathways, key body functions, and health. This will be achieved by combining (1) large-scale harmonization and pooling of existing European cohorts systematically looking at multiple exposures and diseases, with (2) the collection of new high-resolution external and internal exposure data. Methods and tools to characterize the working life exposome will be developed and applied, including sensors, wearables, a harmonized job exposure matrix (EuroJEM), noninvasive biomonitoring, omics, data mining, and (bio)statistics. The toolbox of developed methods and knowledge will be made available to policy makers, occupational health practitioners, and scientists. Advanced knowledge on working life exposures in relation to NCDs will serve as a basis for evidence-based and cost-effective preventive policies and actions. The toolbox will also enable future scientists to further expand the working life exposome knowledge base.
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