ReviewLaryngoscope investigative otolaryngology2022
Is obstructive sleep apnea associated with erythrocytosis? A systematic review and meta-analysis.
Review in Laryngoscope investigative otolaryngology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- HbA1c reconsidered: glycated haemoglobin in the era of dynamic erythrocyte glucose metabolism.Acta diabetologica · 2026Article
- Development and Validation of Prediction Models for Severe Obstructive Sleep Apnea Based on Periodic Health Examinations.The clinical respiratory journal · 2026Article
- Impact of obstructive sleep apnea on hematocrit levels and erythrocytosis - a clinical study.Sleep & breathing = Schlaf & Atmung · 2025Article
- Prevalence of Obstructive Sleep Apnea Among Patients with Secondary Polycythemia: A Retrospective Cross-sectional Study.Oman medical journal · 2025Article
- Exploring the link between comorbid insomnia and sleep apnea (COMISA) and erectile dysfunction: implications for male sexual health.Sexual medicine reviews · 2025Review
- Association of Serum Ferritin Levels With Obstructive Sleep Apnea in Overweight/Obese US Populations: A Population-Based Study From the NHANES.Nature and science of sleep · 2025Article
- COVID-19 and silent hypoxemia in a minimal closed-loop model of the respiratory rhythm generator.Biological cybernetics · 2024Article
- Diagnostic significance of peripheral blood indices for eosinophilic chronic rhinosinusitis in Chinese adults.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Article
- Ferritin is a potential marker of cardiometabolic risk in adolescents and young adults with sleep-disordered breathing.Sleep advances : a journal of the Sleep Research Society · 2024Article
- Prevalence and predictive factors of testosterone-induced erythrocytosis: a retrospective single center study.Frontiers in endocrinology · 2024Observational
- Is obstructive sleep apnea associated with erythrocytosis? A systematic review and meta-analysis.Laryngoscope investigative otolaryngology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: The aim of this systematic review and meta-analysis was to investigate the association between obstructive sleep apnea (OSA) and erythrocytosis. Methods: The PubMed, Web of Science, and Cochrane Library databases were searched for articles examining hematocrit values in patients with OSA and control individuals published till September 1, 2021. The pooled standardized mean difference (SMD) with 95% confidence interval (CI) was calculated, and subgroup analyses were performed. Results: Eleven eligible studies with a total of 4608 patients with OSA were included in this meta-analysis. Pooled outcomes revealed that hematocrit values were significantly higher in patients with OSA than in controls (SMD, 0.19; 95% CI, 0.08-0.29; Conclusion: Our meta-analysis revealed that the hematocrit value was significantly increased in patients with OSA, particularly in severe patients, compared with that in controls. However, the elevation was modest, and the hematocrit value is expected to be within the normal range in patients with OSA. These data suggest that OSA leads to slight increases in hematocrit but does not cause clinically significant erythrocytosis.
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Registered trials
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