Evidence map›Paper›PMID 35434319›Full record

ArticleLaryngoscope investigative otolaryngology2022

Clinical characteristics of patients with CRSwNP with intensely high eosinophil level.

Ling Ma, Jianbo Shi, Kanghua Wang, Yueqi Sun, Rui Xu

Abstract read
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Heterogeneity in the definition of chronic rhinosinusitis disease control: a systematic review of the scientific literature.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Pooled it
  3. [Curative effect analysis of radical endoscopic sinus surgery for eosinophilic chronic rhinosinusitis with nasal polyps].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2023
    Trial
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  8. Review
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  10. Immune endotyping and gene expression profile of patients with chronic rhinosinusitis with nasal polyps in the aspirin-exacerbated respiratory disease (AERD) and the non-AERD subgroups.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2024
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  12. Practical recommendations for managing severe chronic rhinosinusitis with nasal polyps in the era of biologics.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2023
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  14. Care for Patients with Type-2 Chronic Rhinosinusitis.Journal of personalized medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ling MaJinan University Guangzhou China.
Jianbo ShiDepartment of Otolaryngology The First Affiliated Hospital of Sun Yat-sen University Guangzhou China.
Kanghua WangDepartment of Otolaryngology The First Affiliated Hospital of Sun Yat-sen University Guangzhou China.
Yueqi SunDepartment of Otolaryngology The Seventh Affiliated Hospital of Sun Yat-sen University Shenzhen China.ORCID https://orcid.org/0000-0002-2382-0429
Rui XuDepartment of Otolaryngology The First Affiliated Hospital of Sun Yat-sen University Guangzhou China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: High tissue and blood eosinophils are linked to poor treatment outcome in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). However, the difference between the patients with different level of blood or tissue eosinophilia in relation to disease control is still lacking. Objectives: This study aimed to characterize patients with CRSwNP with intensely high eosinophil level. Methods: A retrospective study of CRSwNP patients underwent endoscopic sinus surgery was conducted. The patients were subdivided with various cut-off values of blood and tissue eosinophils. Tissue eosinophils of ≥50% and 10%-20% were defined as intensely high tissue eosinophils (IH-tissue-eos) and high tissue eosinophils (H-tissue-eos), respectively. Blood eosinophils of ≥0.6 × 10 Results: A total of 302 patients were enrolled. There was a trend toward a higher rate of uncontrolled disease when the patients subdivided by blood eosinophil cut-off values ranged from 0.1 × 10 Conclusion: CRSwNP patients with IH-blood-eos (≥0.6 × 10

Indexed as

disease controleosinophilnasal polyprhinosinusitis

Identifiers

PMID35434319
PMCPMC9008161

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.