Evidence map›Paper›PMID 35434143›Full record

ReviewJournal of immunology research2022

miR-155: An Important Role in Inflammation Response.

Jingyan Hu, Songli Huang, Xiaoli Liu, Yuan Zhang, Shengli Wei, Xiuhua Hu

Open access · goldAbstract readReview
In one paragraph

Review in Journal of immunology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed, 3 pooled it
13.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

100 citing papers in PubMed, 3 syntheses or guidelines pooled it, 143 citations in OpenAlex.

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  8. Lack of Association BetweenInternational journal of molecular sciences · 2026
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40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jingyan HuSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing 102400, China.ORCID https://orcid.org/0000-0003-4594-3152
Songli HuangSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing 102400, China.ORCID https://orcid.org/0000-0002-0640-5637
Xiaoli LiuXi'an Children's Hospital, Xi'an 710003, China.ORCID https://orcid.org/0000-0002-2648-7115
Yuan ZhangSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102400, China.ORCID https://orcid.org/0000-0003-2341-8912
Shengli WeiSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102400, China.ORCID https://orcid.org/0000-0003-1442-7120
Xiuhua HuSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing 102400, China.ORCID https://orcid.org/0000-0001-8599-3627
Beijing University of Chinese Medicine · CNXi’an Children’s Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) are a class of small, mature, noncoding RNA that lead to posttranscriptional gene silencing to regulate gene expression. miRNAs are instrumental in biological processes such as cell development, cell differentiation, cell proliferation, and cell apoptosis. The miRNA-mediated gene silencing is an important part of the regulation of gene expression in many kinds of diseases. miR-155, one of the best-characterized miRNAs, has been found to be closely related to physiological and pathological processes. What is more, miR-155 can be used as a potential therapeutic target for inflammatory diseases. We analyze the articles about miR-155 for nearly five years, review the advanced study on the function of miR-155 in different inflammatory cells like T cells, B cells, DCs, and macrophages, and then summarize the biological functions of miR-155 in different inflammatory cells. The widespread involvement of miR-155 in human diseases has led to a novel therapeutic approach between Chinese and Western medicine.

Indexed as

MicroRNAsCell DifferentiationHumansInflammationMacrophagesRNA InterferenceMicroRNAsMIRN155 microRNA, human

Identifiers

PMID35434143
PMCPMC9007653
OpenAlexW4226225780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.