Evidence map›Paper›PMID 35433791›Full record

ArticleFrontiers in nutrition2022

Association Between Riboflavin Intake and Telomere Length: A Cross-Sectional Study From National Health and Nutrition Examination Survey 1999-2002.

Weihua Chen, Shanshan Shi, Yizhou Jiang, Liling Chen, Ying Liao, Kaihong Chen, Kun Huang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Weihua ChenLongyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Shanshan ShiLongyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Yizhou JiangState Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Liling ChenLongyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Ying LiaoLongyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Kaihong ChenLongyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Kun HuangCenter for Statistical Science, Department of Industrial Engineering, Tsinghua University, Beijing, China.
Fujian Medical University · CNFirst Affiliated Hospital of Fujian Medical University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNTsinghua University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Dietary habits and dietary intake affect telomere length, a reliable marker of biological aging and a predictor of chronic disease. Riboflavin (RF) is known as a water-soluble antioxidant vitamin, but its role in telomere length maintenance has yet to be elucidated. Objective: The purpose of this study was to examine the relationship between dietary RF intake and telomere length in a nationally representative sample of adults. Methods: Using the NHANES (1999-2002), telomere data of 4,298 participants aged ≥45 years were analyzed in a cross-sectional manner. Leukocyte telomere length was measured using the quantitative real-time polymerase chain reaction (qPCR). Dietary RF intake was assessed by a trained interviewer using 24-h dietary recall method. Generalized linear regressions were performed to evaluate the association between dietary RF intake and telomere length. Subgroup analyses were performed to further explore this relationship in sex and body mass index (BMI) subgroups. Results: Among the 3,788 participants included, the average telomere length was longer in females ( Conclusion: Increased dietary RF intake was significantly associated with longer telomere length in middle-aged and older American females, especially in low RF intake obese female.

Indexed as

dietary intakefemaleNHANESobeseriboflavintelomere length

Identifiers

PMID35433791
PMCPMC9009291
OpenAlexW4220687472

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.