Evidence map›Paper›PMID 35433708›Full record

ArticleFrontiers in cell and developmental biology2022

Novel Homozygous

Yao Xu, Rongxiang Wang, Zhi Pang, Zhiyun Wei, Lihua Sun, Sa Li, Guanghua Wang, Yu Liu, Yiwen Zhou, Hongjuan Ye and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Structural insight into the function of human peptidyl arginine deiminase 6.Computational and structural biotechnology journal · 2024
    Article
  5. Advances in the genetic etiology of female infertility.Journal of assisted reproduction and genetics · 2024
    Review
  6. Review
  7. Article
  8. PADI6: What we know about the elusive fifth member of the peptidyl arginine deiminase family.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  9. Review
  10. A complex heterozygous mutation inFrontiers in genetics · 2022
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Yao XuShanghai Key Laboratory of Maternal Fetal Medicine, Clinical and Translational Research Center, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
Rongxiang WangReproductive Medicine Center, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
Zhi PangLiver Cancer Institute, Zhongshan Hospital, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Fudan University, Shanghai, China.
Zhiyun WeiShanghai Key Laboratory of Maternal Fetal Medicine, Clinical and Translational Research Center, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
Lihua SunReproductive Medicine Center, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
Sa LiKey Laboratory of Receptor Research, Shanghai Institute of Materia Medica, University of Chinese Academy of Sciences, Beijing, China.
Guanghua WangShanghai Key Laboratory of Maternal Fetal Medicine, Clinical and Translational Research Center, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
Yu LiuReproductive Medicine Center, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
Yiwen ZhouReproductive Medicine Center, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
Hongjuan YeReproductive Medicine Center, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
Liping JinShanghai Key Laboratory of Maternal Fetal Medicine, Clinical and Translational Research Center, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
Songguo XueReproductive Medicine Center, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
Shanghai East Hospital · CNShanghai First Maternity and Infant Hospital · CNFudan University · CNShanghai Institute of Materia Medica · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early embryonic arrest denotes premature termination of development in preimplantation embryos, which is one of the major phenotypes of recurrent assisted reproduction failure. Padi6 is proven to be a member of the subcortical maternal complex (SCMC) in mice, which is essential in oocyte maturation and embryogenesis. We and other groups previously found that biallelic mutations in

Indexed as

early embryonic arrestfemale infertilitynovel variantPADI6subcortical maternal complex

Identifiers

PMID35433708
PMCPMC9010549
OpenAlexW4221028640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.