Evidence map›Paper›PMID 35433694›Full record

ReviewFrontiers in cell and developmental biology2022

Critical Examination of Müller Glia-Derived

Ye Xie, Bo Chen

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ye XieDepartments of Ophthalmology and Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Bo ChenDepartments of Ophthalmology and Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Icahn School of Medicine at Mount Sinai · US

Funding

CaMKII-mediated Neuroprotection of Retinal Ganglion CellsR01EY028921 · NEI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CHEN, BO · 2019 to 2022
$2.4M
Regeneration of rod photoreceptors from Muller glial cells in adult mouse retinaR01EY024986 · NEI · YALE UNIVERSITY · PI CHEN, BO · 2016 to 2019
$1.6M
NEI NIH HHS R01 EY024986NEI NIH HHS R01 EY028921
6 · The paper itself

Abstract

Müller glia (MG) are a potential source of stem cells in the mammalian retina that could replenish lost retinal neurons for vision restoration. Unlike their counterpart in zebrafish, mammalian MG are quiescent and they do not spontaneously generate new retinal neurons. In recent years, extensive research efforts have been made to unlock the regenerative capabilities of Müller glia (MG) for

Indexed as

fate mappingmiceMüller glianeurogenesisretina

Identifiers

PMID35433694
PMCPMC9008276
OpenAlexW4220731756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.