ArticleFrontiers in bioengineering and biotechnology2022
Adaptive Gelatin Microspheres Enhanced Stem Cell Delivery and Integration With Diabetic Wounds to Activate Skin Tissue Regeneration.
Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 41 citations in OpenAlex.
- Hair Follicle Stem Cells: Emerging Physiology and Therapeutic Applications.Stem cell reviews and reports · 2026Review
- Promoting skin regeneration: research progress on hydrogel wound dressings related to scarless healing.Journal of Zhejiang University. Science. B · 2026Review
- Review
- Advanced regenerative solutions in diabetic foot ulcer therapy: delivery of mesenchymal stem cells in injectable hydrogels.Stem cell research & therapy · 2026Review
- Novel approach for diabetic wound healing: adipose-derived mesenchymal stromal cells Exo@SPHydrogel combined with laser therapy.NPJ Regenerative medicine · 2026Article
- Bacteriophage Cocktail in Hydrogel Dressing Modulates Macrophage Responses and Induces Skin Cell Migration.Tissue engineering and regenerative medicine · 2026Article
- Recent advances and challenges in hydrogel-based delivery of immunomodulatory strategies for diabetic wound healing.Theranostics · 2026Review
- Reversing diabetic wound stagnation: macrophage polarization dysregulation as a therapeutic linchpin from pathogenesis to precision interventions.Burns & trauma · 2026Review
- Hydrogel-based neural engineering for skin wound healing.Frontiers in cell and developmental biology · 2026Review
- Synergistic effects of berberine and adipose stem cells in a silk fibroin-PEG hydrogel for diabetic wound healing via macrophage polarization modulation.Regenerative biomaterials · 2026Article
- Mesenchymal stem cell-derived small extracellular vesicles-loaded GelMA microspheres enhance diabetic wound healing by promoting M2 macrophage polarization through p38 MAPK inhibition.Materials today. Bio · 2025Article
- Stem cell-derived exosomes in wound healing: mechanistic insights and delivery strategies.Regenerative medicine · 2025Review
- Hydrogel inspired by "adobe" with antibacterial and antioxidant properties for diabetic wound healing.Materials today. Bio · 2025Article
- Preparation Methods of Hydrogel Microspheres and Recent Advances in Their Application for Treating Diabetic Wounds.International journal of nanomedicine · 2025Review
- Astaxanthin mediated repair of tBHP-Induced cellular injury in chondrocytes.Redox report : communications in free radical research · 2024Article
- Effect of Sinapine on Microstructure and Anti-Digestion Properties of Dual-Protein-Based Hydrogels.Foods (Basel, Switzerland) · 2024Article
- Alternative therapeutic strategies in diabetes management.World journal of diabetes · 2024Review
- Exosomes derived from epidermal growth factor-like domain protein 6-preconditioned mesenchymal stem cells for diabetic wound healing.Regenerative therapy · 2024Article
- Human Mesenchymal Stem Cells on Size-Sorted Gelatin Hydrogel Microparticles Show Enhanced In Vitro Wound Healing Activities.Gels (Basel, Switzerland) · 2024Article
- Enhancing Immunomodulatory Function of Mesenchymal Stromal Cells by Hydrogel Encapsulation.Cells · 2024Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The delayed and complicated diabetic wound healing raises clinical and social concerns. The application of stem cells along with hydrogels is an attractive therapeutic approach. However, low cell retention and integration hindered the performance. Herein, gelatin microspheres were fabricated for local delivery of adipose-derived stem cells (from rats, rADSCs), and the effect of rADSCs with microspheres on diabetic wound healing was examined. Uniform, well-dispersed microspheres were fabricated using the microfluidic technique. Due to geometry differences, the proteinase degradation rate for microspheres was four times that of the bulk hydrogel. The obtained gelatin microspheres supported cell's adhesion and proliferation and provided a suitable microenvironment for rADSC survival. For
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.