Evidence map›Paper›PMID 35433580›Full record

ArticleFrontiers in public health2022

Association Between Depression and Risk of Incident Cardiovascular Diseases and Its Sex and Age Modifications: A Prospective Cohort Study in Southwest China.

Lisha Yu, Yun Chen, Na Wang, Kelin Xu, Chenghan Wu, Tao Liu, Chaowei Fu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 23 citations in OpenAlex.

  1. Depression and Long-Term HbADiabetes/metabolism research and reviews · 2026
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  9. Exploring the Relationship Between Heart, Brain, and Depression.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2025
    Review
  10. Review
  11. Article
  12. Influencing Factors on Cardiovascular Health in China.Journal of geriatric cardiology : JGC · 2024
    Article
  13. Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lisha YuGuizhou Center for Disease Control and Prevention, Guiyang, China.
Yun ChenSchool of Public Health, Key Laboratory of Public Health Safety, National Health Commission Key Laboratory of Health Technology Assessment, Fudan University, Shanghai, China.
Na WangSchool of Public Health, Key Laboratory of Public Health Safety, National Health Commission Key Laboratory of Health Technology Assessment, Fudan University, Shanghai, China.
Kelin XuSchool of Public Health, Key Laboratory of Public Health Safety, National Health Commission Key Laboratory of Health Technology Assessment, Fudan University, Shanghai, China.
Chenghan WuGuizhou Center for Disease Control and Prevention, Guiyang, China.
Tao LiuGuizhou Center for Disease Control and Prevention, Guiyang, China.
Chaowei FuSchool of Public Health, Key Laboratory of Public Health Safety, National Health Commission Key Laboratory of Health Technology Assessment, Fudan University, Shanghai, China.
National Health and Family Planning Commission · CNGuizhou Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To examine possible associations between depression and cardiovascular disease (CVD) incidence and whether demographic factors modified those associations in the Chinese population. This prospective cohort study comprised 7,735 adults aged 18 years or older in Guizhou, China from 2010 to 2020. The Patient Health Questionnaire-9 (PHQ-9) was used to measure the prevalence of depression. Cox proportional hazard models were used to estimated hazard ratios (HRs) and 95% confidence intervals (95%CIs) of depression and incident CVD. We identified 215 CVD cases (including 28 acute myocardial infarction (AMI) and 197 stroke cases) during an average follow-up of 7.07 years. In the multivariable-adjusted model, baseline PHQ-9 score was associated with incident CVD, AMI, and stroke. The HR per 1-SD increase for PHQ-9 score was 1.14 (95%CI: 1.03, 1.26) for CVD, 1.26 (95%CI: 1.01, 1.57) for AMI, and 1.12 (95%CI: 1.01, 1.25) for stroke. Compared with participants without depression, those with any mild or more advanced depression had a higher risk of incident CVD (HR: 1.69, 95%CI: 1.08, 2.64) and AMI (HR: 3.36, 95%CI: 1.17, 10.56). Associations between depression with CVD and stroke were suggested to be even stronger among women and participants aged <65 years (

Indexed as

Cardiovascular DiseasesMyocardial InfarctionStrokeAdultChinaDepressionFemaleHumansMaleProspective StudiesRisk Factorscardiovascular diseasecohort studydepressioneffect modificationthe Patient Health Questionnaire-9 (PHQ-9)

Identifiers

PMID35433580
PMCPMC9005795
OpenAlexW4221051713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.