ReviewFrontiers in pediatrics2022
Management of Acute Kidney Injury in Extremely Low Birth Weight Infants.
Review in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Acute kidney injury magnitude, mortality, and associated factors among neonates in sub-Saharan Africa: a systematic review and meta-analysis.Pediatric nephrology (Berlin, Germany) · 2025Pooled it
- Maintenance intravenous fluid therapy in infants with sepsis and hyponatremia: a clinical trial.BMC pediatrics · 2024Trial
- From Gestational Age-Specific Serum Creatinine Trajectories to an Interactive Clinical Interpretation Tool in Level IV NICU Infants.Research square · 2026Article
- Neonatal acute kidney injury: where are we now?Pediatric nephrology (Berlin, Germany) · 2026Review
- Hyperuricemia in preterm infants: clinical features and early rasburicase therapy.Pediatric research · 2026Article
- Cystatin C as a Renal Biomarker in Infants with Congenital Anomalies of the Kidney and Urinary Tract (CAKUT): A Systematic Review.Diagnostics (Basel, Switzerland) · 2026Review
- Neonatal acute kidney injury: a survey of practices in Canadian neonatal intensive care units.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Kidney care at NICU discharge and follow-up recommendations for preterm infants<34 weeks.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Albumin in neonates: use it or lose it.Pediatric research · 2026Article
- Clinical Determinants and Mortality Predictors of Acute Kidney Injury in Neonates: A Five-Year Retrospective Cohort Study.Sisli Etfal Hastanesi tip bulteni · 2026Article
- The role of serum Neutrophil Gelatinase-Associated Lipocalin (NGAL) in detecting acute kidney injury in preterm neonates exposed to nephrotoxic drugs.BMC pediatrics · 2025Observational
- Fluid Management in ELGANs: Striking the Perfect Balance!Indian journal of pediatrics · 2025Review
- Urinary KIM-1 for Early Detection of Acute Kidney Injury in Neonates: A Systematic Review and Meta-Analysis.Life (Basel, Switzerland) · 2025Review
- Neonatal Kidney Function, Injury and Drug Dosing: A Contemporary Review.Children (Basel, Switzerland) · 2025Review
- Pharmacovigilance of nephrotoxic drugs in neonates: the Pottel method for acute kidney injury detection in ELBW neonates.Pediatric nephrology (Berlin, Germany) · 2024Article
- Acute Kidney Injury in Neonatal Intensive Care Unit: Epidemiology, Diagnosis and Risk Factors.Journal of clinical medicine · 2024Review
- Use of furosemide in preterm neonates with acute kidney injury is associated with increased mortality: results from the TINKER registry.Pediatric nephrology (Berlin, Germany) · 2024Article
- An Interesting Case of Neonatal AKI: What Is the Time to Consider Anuria Irreversible?Children (Basel, Switzerland) · 2023Article
- Prevention of Chronic Morbidities in Extremely Premature Newborns with LISA-nCPAP Respiratory Therapy and Adjuvant Perinatal Strategies.Antioxidants (Basel, Switzerland) · 2023Review
- Acute Kidney Injury in Very Low Birth Weight Infants: A Major Morbidity and Mortality Risk Factor.Children (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute kidney injury (AKI) is a common problem in the neonatal intensive care unit (NICU). Neonates born at <1,000 g (extremely low birth weight, ELBW) are at an increased risk of secondary associated comorbidities such as intrauterine growth restriction, prematurity, volume restriction, ischaemic injury, among others. Studies estimate up to 50% ELBW infants experience at least one episode of AKI during their NICU stay. Although no curative treatment for AKI currently exists, recognition is vital to reduce potential ongoing injury and mitigate long-term consequences of AKI. However, the definition of AKI is imperfect in this population and presents clinical challenges to correct identification, thus contributing to under recognition and reporting. Additionally, the absence of guidelines for the management of AKI in ELBW infants has led to variations in practice. This review summarizes AKI in the ELBW infant and includes suggestions such as close observation of daily fluid balance, review of medications to reduce nephrotoxic exposure, management of electrolytes, maximizing nutrition, and the use of diuretics and/or dialysis when appropriate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.