Evidence map›Paper›PMID 35433456›Full record

ArticleFrontiers in oncology2022

Generation of Tumor-Specific Cytotoxic T Cells From Blood

Adela Kiessling, Keerthana Ramanathan, Ola B Nilsson, Luigi Notari, Stefanie Renken, Rolf Kiessling, Hans Grönlund, Stina L Wickström

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Adela KiesslingDepartment of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Keerthana RamanathanDepartment of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Ola B NilssonDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Luigi NotariDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Stefanie RenkenDepartment of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Rolf KiesslingDepartment of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Hans GrönlundDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Stina L WickströmDepartment of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Karolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For the past decade, adoptive cell therapy including tumor-infiltrating lymphocytes, genetically modified cytotoxic lymphocytes expressing a chimeric antigen receptor, or a novel T-cell receptor has revolutionized the treatment of many cancers. Progress within exome sequencing and neoantigen prediction technologies provides opportunities for further development of personalized immunotherapies. In this study, we present a novel strategy to deliver

Indexed as

autologous tumor recognitiondendritic cell-mediated activationneoantigenpersonalized cancer immunotherapytumor-specific antigens

Identifiers

PMID35433456
PMCPMC9009257
OpenAlexW4220906047

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.