Evidence map›Paper›PMID 35433363›Full record

ArticleAnnals of cardiothoracic surgery2022

Pulmonary thromboendarterectomy for chronic thromboembolic pulmonary hypertension: a systematic review.

John D L Brookes, Crystal Li, Sally T W Chung, Elizabeth M Brookes, Michael L Williams, Nicholas McNamara, Sofia Martin-Suarez, Antonio Loforte

Open access · diamondAbstract read
In one paragraph

Article in Annals of cardiothoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

John D L BrookesDepartment of Cardiothoracic Surgery, University Hospital Geelong, Barwon Health, Geelong, Australia.
Crystal LiThe Collaborative Research (CORE) Group, Macquarie University, Sydney, Australia.
Sally T W ChungThe Collaborative Research (CORE) Group, Macquarie University, Sydney, Australia.
Elizabeth M BrookesDepartment of Medicine, St Vincent's Hospital, Melbourne, Australia.
Michael L WilliamsThe Collaborative Research (CORE) Group, Macquarie University, Sydney, Australia.
Nicholas McNamaraThe Collaborative Research (CORE) Group, Macquarie University, Sydney, Australia.
Sofia Martin-SuarezS. Orsola University Hospital, IRCCS Bologna, Division of Cardiac Surgery, Bologna, Italy.
Antonio LoforteS. Orsola University Hospital, IRCCS Bologna, Division of Cardiac Surgery, Bologna, Italy.
Collaborative Research Group · AUBarwon Health · AUMacquarie University · AURoyal Prince Alfred Hospital · AUSt Vincent's Hospital Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pulmonary thromboendarterectomy (PTE) is the gold standard treatment for patients with chronic thromboembolic pulmonary hypertension (CTEPH). However, the results are poorly quantified outside a few registry reports and several individual centers. Methods: A systematic review was performed searching five electronic databases assessing the outcomes for adult patients undergoing PTE for CTEPH. All articles that reported mortality data were included. Primary outcome measures were early/inpatient mortality; secondary outcomes were survival, pulmonary haemodynamics, morbidity and functional status following PTE for CTEPH. Results were pooled via a meta-analysis of proportions and meta-regression. Results: A total of 5,717 studies were identified, yielding sixty-one relevant papers. Thirty-day mortality ranged from 0.8% to 24.4%, and on meta-analysis was 8.4% [95% confidence interval (CI): 7.2-9.6%]. Mortality was noted to decrease with increasing center volume of PTE cases (P<0.01). Residual pulmonary hypertension was reported in 8.2% to 44.5% of patients. Conclusions: CTEPH is associated with acceptable short-term mortality and an improvement in pulmonary hemodynamics. With increasing volume of experience and ongoing developments over time peri-operative mortality continues to decrease.

Indexed as

chronic thromboembolic pulmonary hypertension (CTEPH)Pulmonary endarterectomypulmonary hypertensionpulmonary thromboendarterectomy (PTE)

Identifiers

PMID35433363
PMCPMC9012194
OpenAlexW4226042907

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.