Evidence map›Paper›PMID 35433177›Full record

ArticleNanophotonics (Berlin, Germany)2021

Membrane composition is a functional determinant of NIR-activable liposomes in orthotopic head and neck cancer.

Mina Guirguis, Chanda Bhandari, Junjie Li, Menitte Eroy, Sushant Prajapati, Ryan Margolis, Navadeep Shrivastava, Kenneth Hoyt, Tayyaba Hasan, Girgis Obaid

Open access · goldAbstract read
In one paragraph

Article in Nanophotonics (Berlin, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. The clinical ionizable lipid SM-102 enhances photochemical immunogenic cell death by verteporfin-conjugated liposomes and improves survival in vivo.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  2. Article
  3. Article
  4. A Physiochemical,ACS applied bio materials · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Mina GuirguisDepartment of Bioengineering, University of Texas at Dallas, Richardson 75080, Texas, USA.ORCID 0000-0001-6056-6098
Chanda BhandariDepartment of Bioengineering, University of Texas at Dallas, Richardson 75080, Texas, USA.
Junjie LiDepartment of Bioengineering, University of Texas at Dallas, Richardson 75080, Texas, USA.
Menitte EroyDepartment of Bioengineering, University of Texas at Dallas, Richardson 75080, Texas, USA.
Sushant PrajapatiDepartment of Bioengineering, University of Texas at Dallas, Richardson 75080, Texas, USA.
Ryan MargolisDepartment of Bioengineering, University of Texas at Dallas, Richardson 75080, Texas, USA.
Navadeep ShrivastavaDepartment of Bioengineering, University of Texas at Dallas, Richardson 75080, Texas, USA.
Kenneth HoytDepartment of Bioengineering, University of Texas at Dallas, Richardson 75080, Texas, USA.
Tayyaba HasanWellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, Boston 02114, Massachusetts, USA; and Division of Health Sciences and Technology, Harvard University and Massachusetts Institute of Technology, Cambridge 02139, Massachusetts, USA.ORCID 0000-0003-0871-6057
Girgis ObaidDepartment of Bioengineering, University of Texas at Dallas, Richardson 75080, Texas, USA.ORCID 0000-0002-9452-4467
The University of Texas at Dallas · USHarvard University · US

Funding

Small Molecule Enhancers of Photodynamic Therapy for Skin CancerP01CA084203 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Brian William Pogue · 2001 to 2026
$27.9M
Ovarian Cancer PDT: Multi-intracellular targeting and Image-guided dosimetryR01CA160998 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI HASAN, TAYYABA · 2011 to 2015
$2.0M
Molecular imaging-directed bioengineering of nanoconjugates as adaptable tumor targeting platformsR00CA215301 · NCI · UNIVERSITY OF TEXAS DALLAS · PI OBAID, GIRGIS · 2020 to 2022
$721k
NCI NIH HHS P01 CA084203NCI NIH HHS R00 CA215301NCI NIH HHS R01 CA160998
6 · The paper itself

Abstract

Near-infrared (NIR)-activable liposomes containing photosensitizer (PS)-lipid conjugates are emerging as tunable, high-payload, and tumor-selective platforms for photodynamic therapy (PDT)-based theranostics. To date, the impact that the membrane composition of a NIR-activable liposome (the chemical nature and subsequent conformation of PS-lipid conjugates) has on their

Indexed as

head and neck cancernanomedicinenear infraredphotodynamic therapytumor delivery

Identifiers

PMID35433177
PMCPMC9012185
OpenAlexW3177925006

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.