Evidence map›Paper›PMID 35432999›Full record

ArticleClinical case reports2022

Improvement of depression in a patient with hypothyroidism and deiodinase polymorphism with LT3 Therapy.

Ziyan S Ahmed, Rinsha P V Sherin, Tatiana L Fonseca, Thanh D Hoang, Mohamed K M Shakir

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. The Physiological Functions and Polymorphisms of Type II Deiodinase.Endocrinology and metabolism (Seoul, Korea) · 2023
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ziyan S AhmedEndocrinology Division Walter Reed National Military Medical Center Bethesda Maryland USA.
Rinsha P V SherinEndocrinology Division Walter Reed National Military Medical Center Bethesda Maryland USA.
Tatiana L FonsecaSection of Adult and Pediatric Endocrinology Diabetes & Metabolism University of Chicago Chicago Illinois USA.
Thanh D HoangEndocrinology Division Walter Reed National Military Medical Center Bethesda Maryland USA.ORCID https://orcid.org/0000-0001-7437-5604
Mohamed K M ShakirEndocrinology Division Walter Reed National Military Medical Center Bethesda Maryland USA.ORCID https://orcid.org/0000-0001-5614-6402
Uniformed Services University of the Health Sciences · USWalter Reed National Military Medical Center · USUniversity of Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a 54-year-old man with treatment-resistant depression (TRD) and hypothyroidism who responded to LT3/LT4 combination, rather than LT4 alone. He was able to discontinue all antidepressant medications eventually. Interestingly, the patient has a DIO2 polymorphism.

Indexed as

depressionhypothyroidismpolymorphismT3

Identifiers

PMID35432999
PMCPMC9005678
OpenAlexW4223930062

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.