Evidence map›Paper›PMID 35432891›Full record

ArticleChemical science2022

Enantioselective synthesis of α-amino ketones through palladium-catalyzed asymmetric arylation of α-keto imines.

Wei Wen, Zhao-Pin Ai, Chang-Lin Yang, Chao-Xing Li, Zhu-Lian Wu, Tian Cai, Qi-Xiang Guo

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 16 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Wei WenChongqing Key Laboratory of Soft-Matter Material Chemistry and Function Manufacturing, School of Chemistry and Chemical Engineering, Southwest University Chongqing 400715 China wenwei1989@swu.edu.cn wzl12@swu.edu.cn qxguo@swu.edu.cn.ORCID https://orcid.org/0000-0001-5100-8545
Zhao-Pin AiChongqing Key Laboratory of Soft-Matter Material Chemistry and Function Manufacturing, School of Chemistry and Chemical Engineering, Southwest University Chongqing 400715 China wenwei1989@swu.edu.cn wzl12@swu.edu.cn qxguo@swu.edu.cn.
Chang-Lin YangChongqing Key Laboratory of Soft-Matter Material Chemistry and Function Manufacturing, School of Chemistry and Chemical Engineering, Southwest University Chongqing 400715 China wenwei1989@swu.edu.cn wzl12@swu.edu.cn qxguo@swu.edu.cn.
Chao-Xing LiChongqing Key Laboratory of Soft-Matter Material Chemistry and Function Manufacturing, School of Chemistry and Chemical Engineering, Southwest University Chongqing 400715 China wenwei1989@swu.edu.cn wzl12@swu.edu.cn qxguo@swu.edu.cn.
Zhu-Lian WuChongqing Key Laboratory of Soft-Matter Material Chemistry and Function Manufacturing, School of Chemistry and Chemical Engineering, Southwest University Chongqing 400715 China wenwei1989@swu.edu.cn wzl12@swu.edu.cn qxguo@swu.edu.cn.ORCID https://orcid.org/0000-0001-8444-4028
Tian CaiChongqing Key Laboratory of Soft-Matter Material Chemistry and Function Manufacturing, School of Chemistry and Chemical Engineering, Southwest University Chongqing 400715 China wenwei1989@swu.edu.cn wzl12@swu.edu.cn qxguo@swu.edu.cn.
Qi-Xiang GuoChongqing Key Laboratory of Soft-Matter Material Chemistry and Function Manufacturing, School of Chemistry and Chemical Engineering, Southwest University Chongqing 400715 China wenwei1989@swu.edu.cn wzl12@swu.edu.cn qxguo@swu.edu.cn.ORCID https://orcid.org/0000-0002-0405-7958
Southwest University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chiral α-amino ketones are common structural motifs in natural products and pharmaceuticals, as well as important synthons in organic synthesis. Thus, establishing efficient methods for preparing compounds with these privileged scaffolds is an important endeavor in synthetic chemistry. Herein we disclose a new catalytic asymmetric approach for the synthesis of chiral α-amino ketones through a chiral palladium-catalyzed arylation reaction of

Identifiers

PMID35432891
PMCPMC8966749
OpenAlexW4224298897

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.