Evidence map›Paper›PMID 35432565›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2022

Isoflavones from Semen Sojae Preparatum Improve Atherosclerosis and Oxidative Stress by Modulating Nrf2 Signaling Pathway through Estrogen-Like Effects.

Jinzhou Guo, Jingxin Ma, Kun Cai, Haining Chen, Ke Xie, Binren Xu, Desen Quan, Jingyan Du

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Targeted drug delivery systems for atherosclerosis.Journal of nanobiotechnology · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Phytochemicals in Cancer Chemoprevention: Preclinical and Clinical Studies.Cancer control : journal of the Moffitt Cancer Center
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jinzhou GuoGuizhou University of Traditional Chinese Medicine, Gui Yang 550025, China.ORCID https://orcid.org/0000-0001-8810-7766
Jingxin MaGuizhou University of Traditional Chinese Medicine, Gui Yang 550025, China.ORCID https://orcid.org/0000-0002-5775-5477
Kun CaiGuizhou University of Traditional Chinese Medicine, Gui Yang 550025, China.ORCID https://orcid.org/0000-0001-6352-2779
Haining ChenGuizhou University of Traditional Chinese Medicine, Gui Yang 550025, China.
Ke XieGuizhou University of Traditional Chinese Medicine, Gui Yang 550025, China.
Binren XuGuizhou University of Traditional Chinese Medicine, Gui Yang 550025, China.
Desen QuanGuizhou University of Traditional Chinese Medicine, Gui Yang 550025, China.
Jingyan DuGuizhou University of Traditional Chinese Medicine, Gui Yang 550025, China.
Guizhou University · CNJiangxi University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis (AS) often occurs in cardiovascular disease, which is a chronic vascular disease and is harmful to human health. Oxidative stress is involved in its etiology. This study aimed to determine the effectiveness of Isoflavones from semen sojae preparatum (ISSP) in inhibiting oxidative stress and its important molecular mechanisms through in vivo and in vitro experiments. ApoE

Identifiers

PMID35432565
PMCPMC9010186
OpenAlexW4225909329

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.