Evidence map›Paper›PMID 35432478›Full record

ArticleFrontiers in genetics2022

Prenatal Exposures to Common Phthalates and Prevalent Phthalate Alternatives and Infant DNA Methylation at Birth.

Rebekah L Petroff, Vasantha Padmanabhan, Dana C Dolinoy, Deborah J Watkins, Joseph Ciarelli, Diana Haggerty, Douglas M Ruden, Jaclyn M Goodrich

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Rebekah L PetroffDepartment of Environmental Health Sciences, University of Michigan, Ann Arbor, MI, United States.
Vasantha PadmanabhanDepartment of Environmental Health Sciences, University of Michigan, Ann Arbor, MI, United States.
Dana C DolinoyDepartment of Environmental Health Sciences, University of Michigan, Ann Arbor, MI, United States.
Deborah J WatkinsDepartment of Environmental Health Sciences, University of Michigan, Ann Arbor, MI, United States.
Joseph CiarelliDepartment of Pediatrics, University of Michigan, Ann Arbor, MI, United States.
Diana HaggertyScholarly Activities and Scientific Support, Spectrum Health West Michigan, Grand Rapids, MI, United States.
Douglas M RudenDepartment of Obstetrics and Gynecology, Wayne State University, Detroit, MI, United States.
Jaclyn M GoodrichDepartment of Environmental Health Sciences, University of Michigan, Ann Arbor, MI, United States.
University of Michigan–Ann Arbor · USSpectrum Health · USWayne State University · US

Funding

Statistical Services and Methods Development ResourceU2CES026555 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GENNINGS, CHRIS · 2015 to 2025
$26.4M
Understanding Breastfeeding Practices Among ECHO Cohort Participants Before and During/After the COVID-19 PandemicUH3OD023285 · OD · MICHIGAN STATE UNIVERSITY · PI Charles James Barone, MICHAEL R. ELLIOTT · 2018 to 2026
$24.5M
Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3M
Strategic Vision & Impact on Environmental HealthP30ES017885 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Dana Dolinoy · 2011 to 2026
$21.3M
Prenatal Exposures and Child Health Outcomes: A Statewide StudyUG3OD023285 · OD · MICHIGAN STATE UNIVERSITY · PI BARONE, CHARLES JAMES, ELLIOTT, MICHAEL R. · 2016 to 2024
$12.9M
ENVIRONMENTAL TOXICOLOGY PRE/POST DOCTORAL RES.TRAININGT32ES007062 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Justin Adam Colacino · 1985 to 2026
$10.5M
Pilot Project ProgramP30ES020957 · NIEHS · WAYNE STATE UNIVERSITY · PI RUDEN, DOUGLAS M · 2014 to 2021
$10.1M
Untargeted Analysis ResourceU2CES026553 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MEEKER, JOHN D. · 2015 to 2015
$9.5M
Environmental Epigenomics and Precision Environmental HealthR35ES031686 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Dana Dolinoy · 2020 to 2026
$6.1M
Project 3: Developmental Exposures and Diet: Epigenetics of Metabolic SyndromeP01ES022844 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PADMANABHAN, VASANTHA, PETERSON, KAREN EILEEN · 2013 to 2018
$3.9M
NovaSeq Shared Instrumentation Grant for Wayne State UniversityS10OD025170 · OD · WAYNE STATE UNIVERSITY · PI RUDEN, DOUGLAS M · 2018 to 2018
$600k
Effects of Lead on Neuronal Differentiation in Human Embryonic Stem CellsR21ES021983 · NIEHS · WAYNE STATE UNIVERSITY · PI RUDEN, DOUGLAS M · 2012 to 2013
$413k
NIDDK NIH HHS P30 DK020572NIEHS NIH HHS L30 ES033406NIEHS NIH HHS P01 ES022844NIEHS NIH HHS P30 ES017885NIEHS NIH HHS P30 ES020957NIEHS NIH HHS R21 ES021983NIEHS NIH HHS R35 ES031686NIEHS NIH HHS T32 ES007062NIEHS NIH HHS U2C ES026553NIEHS NIH HHS U2C ES026555NIH HHS S10 OD025170NIH HHS UG3 OD023285NIH HHS UH3 OD023285
6 · The paper itself

Abstract

Phthalates are a diverse group of chemicals used in consumer products. Because they are so widespread, exposure to these compounds is nearly unavoidable. Recently, growing scientific consensus has suggested that phthalates produce health effects in developing infants and children. These effects may be mediated through mechanisms related to the epigenome, the constellation of mitotically heritable chemical marks and small compounds that guide transcription and translation. The present study examined the relationship between prenatal, first-trimester exposure of seven phthalates and epigenetics in two pregnancy cohorts (

Indexed as

developmentDNA methylationDOHADepigeneticsphthalates

Identifiers

PMID35432478
PMCPMC9010032
OpenAlexW4220921568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.