Evidence map›Paper›PMID 35432347›Full record

ReviewFrontiers in immunology2022

Transcriptional Regulation of Early T-Lymphocyte Development in Thymus.

Xueyang Bao, Yingyu Qin, Linrong Lu, Mingzhu Zheng

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Development of αβ and γδ T Cells in the Thymus and Methods of Analysis.International journal of molecular sciences · 2025
    Review
  3. Modification ofAnimals : an open access journal from MDPI · 2025
    Article
  4. Thymic Bmi-1 hampers γδT17 generation and its derived RORγt-IL-17A signaling to delay cardiac aging.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Review
  6. Transcriptional network dynamics in early T cell development.The Journal of experimental medicine · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xueyang BaoDepartment of Pathogenic Biology and Immunology, Jiangsu Provincial Key Laboratory of Critical Care Medicine, School of Medicine, Southeast University, Nanjing, China.
Yingyu QinDepartment of Pathogenic Biology and Immunology, Jiangsu Provincial Key Laboratory of Critical Care Medicine, School of Medicine, Southeast University, Nanjing, China.
Linrong LuShanghai Immune Therapy Institute, Renji Hospital, Jiao Tong University School of Medicine, Shanghai, China.
Mingzhu ZhengDepartment of Pathogenic Biology and Immunology, Jiangsu Provincial Key Laboratory of Critical Care Medicine, School of Medicine, Southeast University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

T-lymphocytes play crucial roles for maintaining immune homeostasis by fighting against various pathogenic microorganisms and establishing self-antigen tolerance. They will go through several stages and checkpoints in the thymus from progenitors to mature T cells, from CD4

Indexed as

CD4 AntigensReceptors, Antigen, T-Cell, alpha-betaAnimalsCD8 AntigensMiceReceptors, Antigen, T-CellT-LymphocytesCD4 AntigensCD8 AntigensReceptors, Antigen, T-CellReceptors, Antigen, T-Cell, alpha-betadouble negative (DN) cellsdouble positive (DP) cellssingle positive (SP) cellsT cell receptor (TCR)T-lymphocytestranscriptional regulators

Identifiers

PMID35432347
PMCPMC9008359

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.