Evidence map›Paper›PMID 35432342›Full record

ArticleFrontiers in immunology2022

TLR2 Activation by

Aleksandra Wielento, Grzegorz P Bereta, Katarzyna B Łagosz-Ćwik, Sigrun Eick, Richard J Lamont, Aleksander M Grabiec, Jan Potempa

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Infection and immunity · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Virulence diversity amongJournal of oral microbiology · 2026
    Review
  10. Pathogenesis ofFrontiers in cellular and infection microbiology · 2026
    Review
  11. Article
  12. Article
  13. Macrophage activation and invasion byJournal of oral microbiology · 2026
    Article
  14. Pathogenicity ofFrontiers in cellular and infection microbiology · 2026
    Article
  15. International journal of molecular sciences · 2025
    Article
  16. Article
  17. International journal of molecular sciences · 2025
    Article
  18. Article
  19. Review
  20. Outer membrane vesicles ofFrontiers in microbiology · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Aleksandra WielentoDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.
Grzegorz P BeretaDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.
Katarzyna B Łagosz-ĆwikDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.
Sigrun EickDepartment of Periodontology, Laboratory of Oral Microbiology, School of Dental Medicine, University of Bern, Bern, Switzerland.
Richard J LamontDepartment of Oral Immunology and Infectious Diseases, School of Dentistry, University of Louisville, Louisville, KY, United States.
Aleksander M GrabiecDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.
Jan PotempaDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.
Jagiellonian University · PLUniversity of Louisville · USUniversity of Bern · CH

Funding

Bacterial peptidylarginine deiminase, a link between gums and joint diseaseR01DE022597 · NIDCR · UNIVERSITY OF LOUISVILLE · PI POTEMPA, JAN S · 2013 to 2023
$3.7M
NIDCR NIH HHS R01 DE022597
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

PeriodontitisPorphyromonas gingivalisDinoprostoneHumansProtein-Arginine DeiminasesToll-Like Receptor 2DinoprostoneProtein-Arginine DeiminasesTLR2 protein, humanToll-Like Receptor 2citrullinationfimbriaegingival fibroblastsinflammationpeptidylarginine deiminasePorphyromonas gingivalisreporter cell linesTLR2

Identifiers

PMID35432342
PMCPMC9010743
OpenAlexW4220973836

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.