Evidence map›Paper›PMID 35432221›Full record

ArticleFrontiers in endocrinology2022

Effect of Recombinant Gonadotropin on Testicular Function and Testicular Sperm Extraction in Five Cases of

Jordan Teoli, Vincent Mezzarobba, Lucie Renault, Delphine Mallet, Hervé Lejeune, Pierre Chatelain, Frédérique Tixier, Marc Nicolino, Noël Peretti, Sandrine Giscard D'estaing and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Jordan TeoliService de Biochimie et Biologie Moléculaire, UM Pathologies Endocriniennes, CR DEV-GEN, Centre de Biologie et Pathologie Est, Hospices Civils de Lyon, Bron, France.
Vincent MezzarobbaFédération d'Endocrinologie, Hôpital Louis Pradel, Hospices Civils de Lyon, Bron, France.
Lucie RenaultService de Médecine de la Reproduction, Hôpital Femme-Mère-Enfant, Hospices Civils de Lyon, Bron, France.
Delphine MalletService de Biochimie et Biologie Moléculaire, UM Pathologies Endocriniennes, CR DEV-GEN, Centre de Biologie et Pathologie Est, Hospices Civils de Lyon, Bron, France.
Hervé LejeuneUniversité Claude Bernard Lyon 1, Lyon, France.
Pierre ChatelainUniversité Claude Bernard Lyon 1, Lyon, France.
Frédérique TixierService d'Endocrinologie Pédiatrique, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, Bron, France.
Marc NicolinoUniversité Claude Bernard Lyon 1, Lyon, France.
Noël PerettiUniversité Claude Bernard Lyon 1, Lyon, France.
Sandrine Giscard D'estaingUniversité Claude Bernard Lyon 1, Lyon, France.
Béatrice CuzinChirugie Urologique, Centre Lyonnais d'Urologie Bellecour, Lyon, France.
Frédérique DijoudUniversité Claude Bernard Lyon 1, Lyon, France.
Florence Roucher-BoulezService de Biochimie et Biologie Moléculaire, UM Pathologies Endocriniennes, CR DEV-GEN, Centre de Biologie et Pathologie Est, Hospices Civils de Lyon, Bron, France.
Ingrid PlottonService de Biochimie et Biologie Moléculaire, UM Pathologies Endocriniennes, CR DEV-GEN, Centre de Biologie et Pathologie Est, Hospices Civils de Lyon, Bron, France.
Hospices Civils de Lyon · FRHôpital Femme Mère Enfant · FRInstitut Cellule Souche et Cerveau · FRHôpital Louis Pradel · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Objective: The aim of the study was to investigate the clinical, hormonal, histological, spermiological, and molecular genetic characteristics of a cohort of patients with Patients: We included five patients, including four teenagers, with Results: Bilateral testicular volume increased from 8 ml (interquartile range, 6-9) to 12 ml (10-16) after gonadotropin treatment. Inhibin B levels were relatively stable: 110 ng/L (46-139) before and 91 ng/L (20-120) at the end of gonadotropin treatment. Azoospermia was observed in all semen analyses for all cases during gonadotropin treatment. Three patients agreed to testicular biopsy; no mature sperm cells could be retrieved in any. Conclusion: We characterized a cohort of patients with

Indexed as

Addison DiseaseHypogonadismAdolescentAdultChild, PreschoolChorionic GonadotropinDAX-1 Orphan Nuclear ReceptorHumansMaleReproductive Control AgentsSpermatozoaTestisChorionic GonadotropinDAX-1 Orphan Nuclear ReceptorNR0B1 protein, humanReproductive Control Agentsadrenal hypoplasiaadrenal insufficiencycongenitalgonadotropinhypogonadotrophic hypogonadismmale infertilityspermatogenesistesticular biopsy

Identifiers

PMID35432221
PMCPMC9006945
OpenAlexW4221095058

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.