Evidence map›Paper›PMID 35432045›Full record

ArticleFrontiers in psychiatry2022

Exposure to Olfactory Alcohol Cues During Non-rapid Eye Movement Sleep Did Not Decrease Craving in Patients With Alcohol Dependence.

Ran Zhu, Zhaojun Ni, Ran Tao, Jun Cheng, Liangjun Pang, Shun Zhang, Yang Zhang, Yanxue Xue, Yundong Ma, Wei Sun and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ran ZhuNHC Key Laboratory of Mental Health, Peking University Institute of Mental Health, Peking University Sixth Hospital, Peking University, Beijing, China.
Zhaojun NiNHC Key Laboratory of Mental Health, Peking University Institute of Mental Health, Peking University Sixth Hospital, Peking University, Beijing, China.
Ran TaoNHC Key Laboratory of Mental Health, Peking University Institute of Mental Health, Peking University Sixth Hospital, Peking University, Beijing, China.
Jun ChengAnhui Mental Health Center, Hefei, China.
Liangjun PangAnhui Mental Health Center, Hefei, China.
Shun ZhangKailuan Mental Health Center, Tangshan, China.
Yang ZhangNHC Key Laboratory of Mental Health, Peking University Institute of Mental Health, Peking University Sixth Hospital, Peking University, Beijing, China.
Yanxue XueNational Institute on Drug Dependence, Peking University, Beijing, China.
Yundong MaNHC Key Laboratory of Mental Health, Peking University Institute of Mental Health, Peking University Sixth Hospital, Peking University, Beijing, China.
Wei SunNHC Key Laboratory of Mental Health, Peking University Institute of Mental Health, Peking University Sixth Hospital, Peking University, Beijing, China.
Lin LuNHC Key Laboratory of Mental Health, Peking University Institute of Mental Health, Peking University Sixth Hospital, Peking University, Beijing, China.
Jiahui DengNHC Key Laboratory of Mental Health, Peking University Institute of Mental Health, Peking University Sixth Hospital, Peking University, Beijing, China.
Hongqiang SunNHC Key Laboratory of Mental Health, Peking University Institute of Mental Health, Peking University Sixth Hospital, Peking University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: Cue exposure therapy (CET) has been used to reduce alcohol use, but the effect of CET during sleep on alcohol dependence (AD) is unclear. The present study examined the effect of repeated exposure to an olfactory stimulus during non-rapid eye movement (NREM) sleep on cue reactivity and craving in patients with AD. Methods: Thirty-five patients with AD were enrolled according to the Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV). All the subjects were randomly assigned to the experimental or control group. The experimental group was exposed to alcohol odor for 10 min during NREM sleep. The other group (controls) was exposed to water [control stimulus (CtrS)] for 10 min during NREM sleep. Demographic, alcohol-related, and clinical characteristics were collected at baseline. A cue-reactivity test was conducted before and after exposure to evaluate the effect of memory manipulation on acute response to an alcohol stimulus. Results: There were no significant time × group interactions according to the visual analog scale (VAS) score of craving intensity, skin conductance response (SCR), systolic blood pressure (SBP), and diastolic blood pressure (DBP; all Conclusion: Exposure to olfactory alcohol cues during NREM sleep had no significant effect on alcohol craving in subjects with AD during hospitalization.

Indexed as

alcohol dependencealcohol odorcravingcue exposure therapysleep

Identifiers

PMID35432045
PMCPMC9010533

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.