ArticleFrontiers in aging neuroscience2022
Functional Cognitive Disorder Presents High Frequency and Distinct Clinical Profile in Patients With Low Education.
Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neurocognitive performance in functional neurological disorder: A systematic review and meta-analysis.European journal of neurology · 2025Pooled it
- Preliminary Validation of the FCD-Q8 Tool in Functional Cognitive Disorder and Early Alzheimer's Disease: A Biomarker-Verified Case-Control Study.European journal of neurology · 2025Article
- Saccadic eye movements differentiate functional cognitive disorder from mild cognitive impairment.Perception · 2025Article
- Anticholinergic burden and polypharmacy in patients referred from primary care to tertiary dementia centers in Brazil.Dementia & neuropsychologia · 2025Article
- The Cognitive and Neuroimaging for Neurodegenerative Disorders Study (CogNID): design and initial findings from real-world clinical practice.Frontiers in psychiatry · 2025Article
- Functional Cognitive Disorder: diagnostic challenges, clinical features, and future directions in a misunderstood condition.Frontiers in aging neuroscience · 2025Review
- Development of a diagnostic checklist to identify functional cognitive disorder versus other neurocognitive disorders.BMJ neurology open · 2025Article
- Cognitive complaints in older adults in primary care and associated factors.Dementia & neuropsychologia · 2023Article
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Authors and funding
7 authors.
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Abstract
Introduction: Functional Cognitive Disorder (FCD) is a non-degenerative, common cause of memory complaint in patients with high educational levels. FCD has been insufficiently described in individuals with low education. Here, we investigated the frequency of FCD among individuals with low education. Methods: We analyzed retrospectively all new referrals from primary care to a tertiary memory clinic from 2014 to 2021. Final diagnosis, diagnostic work-up, clinical and cognitive testing data were compared between FCD and other diagnoses, grouped as Neurodegenerative Disorders (NDD). A regression model was used to assess the effect of education on the diagnosis. Data is shown in Mean [SD]. Results: A total of 516 individuals (70.76 [10.3] years) with low educational attainment (4.5 [3.94] years) were divided into FCD (146, 28.3%) and NDD. Compared with NDD, FCD patients showed lower age at presentation (66.2 [9.4] vs. 72.6 [10.2], Discussion: Surprisingly, FCD was the most frequent diagnosis in a low educational setting. However, education was not associated with FCD. Individuals presenting FCD showed a distinct clinical profile, including younger age and higher depressive scores. Strategies to identify FCD in primary care settings may benefit both patients and healthcare systems.
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