ArticleFrontiers in neuroscience2022
Study of Sex Differences in Unmedicated Patients With Major Depressive Disorder by Using Resting State Brain Functional Magnetic Resonance Imaging.
Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Neural correlates of peripartum depression: a systematic review, meta-analysis and comparison to major depressive disorder.Molecular psychiatry · 2025Pooled it
- Brain-based Sex Differences in Depression: A Systematic Review of Neuroimaging Studies.Brain imaging and behavior · 2023Pooled it
- Mechanisms Underlying Treatment-Resistant Depression: Exploring Sex-Based Biological Differences.Journal of neurochemistry · 2025Review
- Focus on the sex-specific neural markers in the discrimination of various degrees of depression.Psychoradiology · 2024Article
- Neuro-Vulnerability in Energy Metabolism Regulation: A Comprehensive Narrative Review.Nutrients · 2023Review
- Retinoid homeostasis in major depressive disorder.Translational psychiatry · 2023Article
- The neural basis underlying female vulnerability to depressive disorders.Animal cells and systems · 2023Review
- Advances in Zebrafish as a Comprehensive Model of Mental Disorders.Depression and anxiety · 2023Review
- Sex-dependent effects of early life stress on reinforcement learning and limbic cortico-striatal functional connectivity.Neurobiology of stress · 2023Article
- Sex Differences of the Functional Brain Activity in Treatment-Resistant Depression: A Resting-State Functional Magnetic Resonance Study.Brain sciences · 2022Article
- Characterization of Resting-State Striatal Differences in First-Episode Depression and Recurrent Depression.Brain sciences · 2022Article
- A Study of Differential Resting-State Brain Functional Activity in Males and Females with Recurrent Depressive Disorder.Brain sciences · 2022Article
- No Sex Differences in Self-Reported Childhood Maltreatment in Major Depressive and Bipolar Disorders: A Retrospective Study.Brain sciences · 2022Article
- Gender differences in major depressive disorders: A resting state fMRI study.Frontiers in psychiatry · 2022Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Some important clinical characteristics of major depressive disorder (MDD) differ between sexes. We explored abnormal spontaneous neuronal activity in MDD patients using the amplitude of low-frequency fluctuation (ALFF) and its relationship to clinical manifestations in male and female patients, to seek the neural mechanisms underlying sex-related differences in depression. Twenty-five male MDD patients, 36 female MDD patients, and 25 male and 36 female matched healthy controls (HC) were included. The ALFF difference was investigated among four groups, and partial correlation analysis was used to explore a possible clinical relevance. The main effect results of sex difference were located in the bilateral caudate nucleus and posterior cingulate gyrus.
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