Evidence map›Paper›PMID 35431688›Full record

ArticleIntegrative medicine (Encinitas, Calif.)2022

Clinical Understanding of the Sleep-Immune Connection.

Jeffrey S Bland

Open access · greenAbstract readEditorial
In one paragraph

Article in Integrative medicine (Encinitas, Calif.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Jeffrey S Bland

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The science of sleep is becoming better understood all the time, and here is a fact that has only recently been revealed: sleep and immune system function have a bidirectional relationship. The disturbance of sleep can create an alteration in immune function. The opposite is also true, in that activation of the immune system can create a disturbance in sleep cycling. This dynamic can ultimately create a feed-forward loop of increasing immune dysfunction and sleep disruption. These systems are intimately intertwined. The clinical approach should be to intervene upstream in the regulation of the fundamental systems that control both sleep and immune function. Through the implementation of this approach, the treatment will focus on the cause of the epigenetic modulation of the sleep-immune system imbalance, and not just its effects and symptomatology.

Identifiers

PMID35431688
PMCPMC9005150
OpenAlexW4224306782

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.