Evidence map›Paper›PMID 35431541›Full record

ArticlePatient preference and adherence2022

Adherence to Oral Targeted Anti-Lung Cancer Therapy: A Qualitative Interview Study.

Huiyue Zhou, Xin Wang, Dan Yu, Ruofei Du, Huaisong Wang, Jizhe Zhu, Haoning Zhang, Changying Chen, Tao Wang

Abstract read
In one paragraph

Article in Patient preference and adherence, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Huiyue Zhou *Nursing and Health School, Zhengzhou University, Zhengzhou, Henan, 450001, People's Republic of China.ORCID 0000-0003-0349-2293
Xin Wang *Nursing and Health School, Zhengzhou University, Zhengzhou, Henan, 450001, People's Republic of China.
Dan Yu *Department of Gengral Surgery, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450001, People's Republic of China.
Ruofei DuNursing and Health School, Zhengzhou University, Zhengzhou, Henan, 450001, People's Republic of China.
Huaisong WangUnion Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, People's Republic of China.
Jizhe ZhuNursing and Health School, Zhengzhou University, Zhengzhou, Henan, 450001, People's Republic of China.
Haoning ZhangNursing and Health School, Zhengzhou University, Zhengzhou, Henan, 450001, People's Republic of China.
Changying ChenDepartment of Quality Control, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450001, People's Republic of China.
Tao WangNursing and Health School, Zhengzhou University, Zhengzhou, Henan, 450001, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Oral targeted antineoplastic drugs (OTADs) are becoming more and more acceptable for lung cancer treatment due to their advantages such as the convenience of administration and milder side effects. However, medication adherence represents a major issue for prolonged OTAD treatment. In this study, the factors associated with treatment adherence to OTAD were explored through the Adherence Influencing Factor Framework suggested by WHO. Based on these results, we further examined the potential factors related to social psychological cognition in OTAD adherence in patients with lung cancer. Methods: This qualitative study was conducted in public hospitals in Henan, China. Data were collected through semi-structured interviews with selected lung cancer patients. Face-to-face interviews were audio-recorded and transcribed for thematic analysis. Results: Of the 21 patients interviewed, 17 were males and 4 were females. The analysis of the data led to four themes, ie, patient-related factors (medication-taking introspection, family structure, weigh the pros and cons of OTAD treatment), medication-related factors (medication experience, adverse reactions, information access), physician/nurse-related factors (shared decision making, doctor's reaction, nurse's inquiry) and society-related factors (fear, stigma). Conclusion: Family structure, weigh the pros and cons of OTAD treatment, information access, shared decision making, nurse's inquiry are potential factors affecting OTAD adherence in lung cancer patients. Providing drug information support to patients, inviting patients to join in shared decision-making and strengthening doctor-patient-nurse cooperation are important for improving medication adherence. Further research should be conducted to help healthcare providers to promote the medication adherence of lung cancer patients to OTAD treatment.

Indexed as

lung cancerOTAD adherencequalitative studytargeted cancer therapy

Identifiers

PMID35431541
PMCPMC9012231

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.