Evidence map›Paper›PMID 35431352›Full record

ArticleTetrahedron letters2021

Cytotoxic and antimicrobial drimane meroterpenoids from a fungus of the

Laura Flores-Bocanegra, Mario Augustinović, Huzefa A Raja, Steven J Kurina, Amanda C Maldonado, Joanna E Burdette, Joseph O Falkinham, Cedric J Pearce, Nicholas H Oberlies

Open access · greenAbstract read
In one paragraph

Article in Tetrahedron letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. A Comprehensive Review on Chemical Structures and Bioactivities ofJournal of fungi (Basel, Switzerland) · 2025
    Review
  3. Article
  4. Article
  5. Biosynthesis of Fungal Drimane-Type Sesquiterpene Esters.Angewandte Chemie (International ed. in English) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Laura Flores-BocanegraDepartment of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina 27402, United States.
Mario AugustinovićDepartment of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina 27402, United States.
Huzefa A RajaDepartment of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina 27402, United States.
Steven J KurinaDepartment of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, United States.
Amanda C MaldonadoDepartment of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, United States.
Joanna E BurdetteDepartment of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, United States.
Joseph O FalkinhamDepartment of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, United States.
Cedric J PearceMycosynthetix, Inc., Hillsborough, North Carolina 27278, United States.
Nicholas H OberliesDepartment of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina 27402, United States.
University of North Carolina at Greensboro · USUniversity of Illinois Chicago · USMycosynthetix (United States) · USVirginia Tech · US

Funding

Project 3:Isolation Chemistry of Filamentous Fungi and Biological EvaluationP01CA125066 · NCI · OHIO STATE UNIVERSITY · PI JAMES R FUCHS · 2007 to 2026
$27.2M
Pilot Program CoreP30ES027792 · NIEHS · UNIVERSITY OF CHICAGO · PI Gokhan M. Mutlu, Gail S Prins · 2017 to 2026
$13.6M
NCI NIH HHS P01 CA125066NIEHS NIH HHS P30 ES027792
6 · The paper itself

Abstract

As part of our ongoing research on bioactive fungal metabolites, two new metabolites were isolated from a fungus of the

Indexed as

antimicrobialcytotoxicdasyscyphinsmeroterpenoidsStictidaceae sp.

Identifiers

PMID35431352
PMCPMC9012486
OpenAlexW3129095728

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.