Evidence map›Paper›PMID 35430897›Full record

ArticleJournal of clinical microbiology2022

Optimal Detection of Latent Mycobacterium tuberculosis Infection by Combined Heparin-Binding Hemagglutinin (HBHA) and Early Secreted Antigenic Target 6 (ESAT-6) Whole-Blood Interferon Gamma Release Assays.

V Dirix, N Dauby, M Hites, E Watelet, A Van Praet, A Godefroid, E Petit, M Singh, C Locht, F Mascart and 1 more

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

V DirixLaboratory of Vaccinology and Mucosal Immunity, Université Libre de Bruxellesgrid.4989.c, Brussels, Belgium.
N DaubyDepartment of Infectious Diseases, Centre Hospitalier Universitaire Saint-Pierre, Université Libre de Bruxellesgrid.4989.c, Brussels, Belgium.
M HitesDepartment of Infectious and Tropical Diseases, Hôpital Erasme, Université Libre de Bruxellesgrid.4989.c, Brussels, Belgium.
E WateletDepartment of Pneumology, Clinique St. Anne/St. Remi-CHIREC, Brussels, Belgium.
A Van PraetLaboratory of Vaccinology and Mucosal Immunity, Université Libre de Bruxellesgrid.4989.c, Brussels, Belgium.
A GodefroidLaboratory of Vaccinology and Mucosal Immunity, Université Libre de Bruxellesgrid.4989.c, Brussels, Belgium.
E PetitUniversité de Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U-1019, UMR8204, Center for Infection and Immunity of Lille, Lille, France.
M SinghLionex Diagnostics and Therapeutics, Braunschweig, Germany.
C LochtUniversité de Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U-1019, UMR8204, Center for Infection and Immunity of Lille, Lille, France.
F MascartLaboratory of Vaccinology and Mucosal Immunity, Université Libre de Bruxellesgrid.4989.c, Brussels, Belgium.ORCID 0000-0001-7635-7944
V CorbièreLaboratory of Vaccinology and Mucosal Immunity, Université Libre de Bruxellesgrid.4989.c, Brussels, Belgium.

Funding

European Commission (EC) HEALTH-2009-2.3.2-2Fonds De La Recherche Scientifique - FNRS (FNRS) PDR T.0147.13INNOV-IRIS BrusselsTuberculosis Vaccine Initiative NORAD
6 · The paper itself

Abstract

Optimal detection of latent tuberculosis (TB) infection (LTBI) remains a challenge, although it is essential to reach the goal of TB elimination. Our objective was to develop and clinically evaluate a user-friendly, 24-h, whole-blood (WB) interferon gamma (IFN-γ) release assay (IGRA) improving the detection of LTBI, compared to available tests. One milliliter of blood was divided into four aliquots and

Indexed as

Latent TuberculosisMycobacterium tuberculosisTuberculosisAntigens, BacterialHumansInterferon-gamma Release TestsLectinsAntigens, Bacterialheparin-binding hemagglutininLectinsearly secreted antigenic target 6heparin-binding hemagglutinininterferon gamma release assaylatent tuberculosis infectionwhole blood

Identifiers

PMID35430897
PMCPMC9116186

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.