ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2022
Apportioning archaic variants among modern populations.
Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Long-term isolation and archaic introgression shape functional genetic variation in Near Oceania.Science (New York, N.Y.) · 2026Article
- Recent advances in methods to characterize archaic introgression in modern humans.Genome research · 2026Review
- Article
- Population histories of the Indigenous Adivasi and Sinhalese from Sri Lanka using whole genomes.Current biology : CB · 2025Article
- Neanderthal ancestry through time: Insights from genomes of ancient and present-day humans.Science (New York, N.Y.) · 2024Article
- Computational Genomics and Its Applications to Anthropological Questions.American journal of biological anthropology · 2024Review
- A history of multiple Denisovan introgression events in modern humans.Nature genetics · 2024Review
- More than a decade of genetic research on the Denisovans.Nature reviews. Genetics · 2024Review
- Integrating sex-bias into studies of archaic introgression on chromosome X.PLoS genetics · 2023Article
- A rarefaction approach for measuring population differences in rare and common variation.Genetics · 2023Article
- The impact of modern admixture on archaic human ancestry in human populations.bioRxiv : the preprint server for biology · 2023Article
- A geometric relationship ofPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Human genetic admixture through the lens of population genomics.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- Celebrating 50 years since Lewontin's apportionment of human diversity.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- The background and legacy of Lewontin's apportionment of human genetic diversity.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- Apportioning archaic variants among modern populations.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
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5 authors.
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Abstract
The apportionment of human genetic diversity within and between populations has been measured to understand human relatedness and demographic history. Likewise, the distribution of archaic ancestry in modern populations can be leveraged to better understand the interaction between our species and its archaic relatives. Resolving the interactions between modern and archaic human populations can be difficult, as archaic variants in modern populations have been shaped by genetic drift, bottlenecks and gene flow. Here, we investigate the distribution of archaic variation in Eurasian populations. We find that archaic ancestry coverage at the individual- and population-level present distinct patterns in modern human populations: South Asians have nearly twice the number of population-unique archaic alleles compared with Europeans or East Asians, indicating that these populations experienced differing demographic and archaic admixture events. We confirm previous observations that East Asian individuals have more Neanderthal ancestry than European individuals, but surprisingly, when we compare the number of single nucleotide polymorphisms with archaic alleles found across a population, Europeans have more Neanderthal ancestry than East Asians. We compare these results to simulated models and conclude that these patterns are consistent with multiple admixture events between modern humans and Neanderthals. This article is part of the theme issue 'Celebrating 50 years since Lewontin's apportionment of human diversity'.
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