ArticleBiological psychiatry. Cognitive neuroscience and neuroimaging2022
Belief Updating and Paranoia in Individuals With Schizophrenia.
Article in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 50 citations in OpenAlex.
- Prior Expectations of Volatility Following Psychotherapy for Delusions: A Randomized Clinical Trial.JAMA network open · 2025Trial
- Visual remediation of contrast processing impairments in schizophrenia: A preliminary clinical trial.Schizophrenia research · 2024Trial
- A Dual Prediction Error Populations Model of Schizophrenia Spectrum Disorders: Bridging NMDA Hypofunction and Gain Hyperfunction.Schizophrenia bulletin · 2026Article
- Anhedonia and Anxious Arousal Are Associated With Distinct Expectations About the Statistics of a Volatile Environment.Biological psychiatry global open science · 2026Article
- Characterizing artificial intelligence (AI) psychosis in a large academic medical setting: evidence of the new clinical phenomenon and the vulnerability of those in early phases of psychosis.medRxiv : the preprint server for health sciences · 2026Article
- Internal monitoring deficits attenuate post-error slowing in psychosis-proneness.Schizophrenia research. Cognition · 2026Article
- Psychosis-proneness is associated with reduced cognitive error-monitoring during instrumental learning.Schizophrenia research. Cognition · 2026Article
- Threading the Needle: Practical Considerations for Merging Theory-Driven Computational Psychiatry With Data-Driven Analytics to Enhance Precision Health at Scale.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Review
- Excessive Switching in OCD and Paranoia Arises From Different Deficits in Belief-Updating.Computational psychiatry (Cambridge, Mass.) · 2026Article
- Self-Reflection Protects Behavior from Volatile Beliefs Linked to Paranoia.Computational psychiatry (Cambridge, Mass.) · 2026Article
- Twin differences in the Minnesota Trust Game relate to neural mechanisms of suspiciousness.Cognitive, affective & behavioral neuroscience · 2025Article
- The neural basis for uncertainty processing in hierarchical decision making.Nature communications · 2025Article
- Placebo and nocebo phenomena in schizophrenia spectrum disorders: a narrative review on current knowledge and potential future directions.Psychological medicine · 2025Review
- A counterweight model for understanding and treating persecutory delusions.Psychological medicine · 2025Article
- Belief Updating, Childhood Maltreatment, and Paranoia in Schizophrenia-Spectrum Disorders.Schizophrenia bulletin · 2025Article
- Computational modeling of reversal learning impairments in schizophrenia and bipolar disorder reveals shared failure to exploit rewards.Journal of psychopathology and clinical science · 2025Article
- Distress and Negative Subtypes of Schizophrenia: Identification, Characterization, and Neurostructural Profiles.Schizophrenia bulletin open · 2025Article
- Model-Based Approaches to Investigating Mismatch Responses in Schizophrenia.Clinical EEG and neuroscience · 2025Review
- Reviewing explore/exploit decision-making as a transdiagnostic target for psychosis, depression, and anxiety.Cognitive, affective & behavioral neuroscience · 2024Review
- Online gaming reduces psychological distress in a patient with schizophrenia: A case report.PCN reports : psychiatry and clinical neurosciences · 2024Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundPersecutory delusions are among the most common delusions in schizophrenia and represent the extreme end of the paranoia continuum. Paranoia is accompanied by significant worry and distress. Identifying cognitive mechanisms underlying paranoia is critical for advancing treatment. We hypothesized that aberrant belief updating, which is related to paranoia in human and animal models, would also contribute to persecutory beliefs in individuals with schizophrenia.
methodsBelief updating was assessed in 42 participants with schizophrenia and 44 healthy control participants using a 3-option probabilistic reversal learning task. Hierarchical Gaussian Filter was used to estimate computational parameters of belief updating. Paranoia was measured using the Positive and Negative Syndrome Scale and the revised Green et al. Paranoid Thoughts Scale. Unusual thought content was measured with the Psychosis Symptom Rating Scale and the Peters et al. Delusions Inventory. Worry was measured using the Dunn Worry Questionnaire.
resultsParanoia was significantly associated with elevated win-switch rate and prior beliefs about volatility both in schizophrenia and across the whole sample. These relationships were specific to paranoia and did not extend to unusual thought content or measures of anxiety. We observed a significant indirect effect of paranoia on the relationship between prior beliefs about volatility and worry.
conclusionsThis work provides evidence that relationships between belief updating parameters and paranoia extend to schizophrenia, may be specific to persecutory beliefs, and contribute to theoretical models implicating worry in the maintenance of persecutory delusions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.